Active Pharmaceutical Ingredient

Rifaximin

Also known as: Xifaxan; L-105; DL 473

CAS: 80621-81-4 Non-Absorbable Antibiotic IP / BP / EP / USP GMP Certified Aurangabad, Maharashtra, India
Rifaximin API — Mediocon Inc
Rifaximin — Pharmaceutical Grade API

Product Overview

CAS No: 80621-81-4  |  MF: C₄₃H₅₁N₃O₁₁  |  MW: 785.88 g/mol

Rifaximin is a pharmaceutical-grade active ingredient classified as a Non-Absorbable Rifamycin Antibiotic. Mediocon Inc supplies high-purity Rifaximin API conforming to IP / BP / EP / USP specifications, manufactured in our GMP-certified facility in Aurangabad, Maharashtra, India.

Rifaximin is a semi-synthetic, non-systemic rifamycin-derived antibiotic that acts locally in the gastrointestinal tract. Due to its minimal systemic absorption, it provides targeted antimicrobial activity against gram-positive and gram-negative bacteria in the gut. It is used for traveler's diarrhea, hepatic encephalopathy, and irritable bowel syndrome with predominant diarrhea.

Key Features

  • High-purity pharmaceutical grade API
  • IP/BP/EP/USP compliant
  • Full CoA and MSDS documentation
  • GMP certified manufacturing

Applications

  • Traveler's diarrhea (non-invasive E. coli)
  • Hepatic encephalopathy prevention and treatment
  • Irritable bowel syndrome with diarrhea (IBS-D)
  • Small intestinal bacterial overgrowth (SIBO)

Why Choose Mediocon

  • ISO 9001:2015 & GMP certified manufacturing
  • Consistent batch-to-batch quality with full CoA
  • Export-ready documentation: COO, MSDS, DMF
  • Flexible MOQ for both R&D and commercial scale
  • Dedicated QA support for regulatory filings

Product Specifications

Product NameRifaximin
Also Known AsXifaxan; L-105; DL 473
CAS Number80621-81-4
Molecular FormulaC₄₃H₅₁N₃O₁₁
Molecular Weight785.88 g/mol
CategoryNon-Absorbable Antibiotic — Rifamycin Derivative
AppearanceLight orange to orange crystalline powder
SolubilityPractically insoluble in water; slightly soluble in methanol
GradeIP / BP / EP / USP

Analytical Specifications

ParameterSpecification
AssayNLT 98.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 20 ppm
Residue on IgnitionNMT 0.1%
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Packing25 kg HDPE drums / as per requirement
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