MEDIOCON INC offers ActivAMP®, a specialized botanical ingredient derived from Gynostemma pentaphyllum, an adaptogenic herb traditionally used in Asia.
ActivAMP® is standardized to two key saponins, Gypenoside L and 20(S)-Ginsenoside Rg3, providing a defined botanical profile for modern nutraceutical and metabolic-health formulations.
ActivAMP® has been researched for its relationship with AMPK, or AMP-activated protein kinase, a cellular energy-regulation pathway involved in glucose utilization, lipid metabolism and energy balance. The ingredient is positioned for metabolic-health, weight-management, sports-performance and healthy-aging formulations.
ActivAMP® is a proprietary Gynostemma pentaphyllum extract developed as a standardized botanical ingredient. The extract is produced from Gynostemma pentaphyllum and standardized to Gypenoside L and 20(S)-Ginsenoside Rg3.
The ingredient is intended for manufacturers developing premium nutraceutical products focused on metabolic health, energy metabolism, physical performance and healthy weight-management applications.
A randomized, double-blind, placebo-controlled study investigated 225 mg of ActivAMP® twice daily, providing 450 mg/day, for 16 weeks in overweight adults. The study reported reductions in body weight, BMI and total fat mass compared with placebo.
ActivAMP® may be incorporated into:
ActivAMP® is positioned around AMPK-related metabolic regulation. AMPK is involved in cellular energy sensing and metabolic pathways, including glucose and lipid utilization.
For commercial product positioning, suitable wording includes:
Avoid presenting ActivAMP® as a treatment or cure for obesity, diabetes or other diseases.
ActivAMP® has been investigated in human clinical research. A 2022 randomized, double-blind, placebo-controlled study evaluated 117 overweight adults receiving 225 mg ActivAMP® twice daily for 16 weeks. The study reported significant reductions in body weight, BMI and total fat mass compared with placebo.
Another human study investigated Gynostemma pentaphyllum supplementation and exercise performance, using 225 mg of dried leaf extract per capsule.
MEDIOCON INC can support sourcing requirements with product-related technical documentation, subject to availability and the applicable supplier specification.
Typical documentation may include:
Store in a cool, dry place in tightly closed original packaging. Protect from moisture, excessive heat and direct sunlight. Follow the manufacturer's current storage and handling instructions.
Packaging should be confirmed according to the required quantity, grade, specification and commercial requirements.
ActivAMP® provides a standardized Gynostemma pentaphyllum extract with a defined saponin profile based on Gypenoside L and 20(S)-Ginsenoside Rg3. Its standardized botanical composition and human research background make it suitable for innovative metabolic-health, sports-nutrition and weight-management formulations.
MEDIOCON INC supports customers seeking specialized nutraceutical ingredients with appropriate technical, quality and regulatory documentation.
| Parameter | Specification |
|---|---|
| Appearance | Fine botanical extract powder |
Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying ActivAMP® Manufacturer & Supplier in India | MEDIOCON INC and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.
Our ActivAMP® Manufacturer & Supplier in India | MEDIOCON INC is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.
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