Active Pharmaceutical Ingredient

Adapalene

Also known as: Differin

CAS: 106685-40-9 Topical Retinoid USP / EP Bulk Supply Available
Adapalene API Manufacturer India | Mediocon Inc
Adapalene — Pharmaceutical Grade API

Product Overview

CAS No: 106685-40-9  |  MF: C₂₈H₂₈O₃  |  MW: 412.52 g/mol

Adapalene is a third-generation topical retinoid used in the treatment of acne vulgaris. It normalizes the differentiation of follicular epithelial cells and has anti-inflammatory properties. Mediocon Inc supplies pharmaceutical-grade Adapalene suitable for gel, cream, and lotion formulations.

Key Features

  • Third-generation topical retinoid
  • USP/EP compliant quality
  • Anti-inflammatory & comedolytic
  • Photostable – suitable for topical use

Applications

  • Acne vulgaris topical gel/cream
  • Combination anti-acne formulations
  • Blackhead and comedone treatment
  • Wrinkle reduction cosmeceuticals

Why Choose Mediocon

  • ISO 9001:2015 & GMP certified manufacturing
  • Consistent batch-to-batch quality with full CoA
  • Export-ready documentation: COO, MSDS, DMF
  • Flexible MOQ for both R&D and commercial scale
  • Dedicated QA support for regulatory filings

Product Specifications

Product NameAdapalene
Also Known AsDifferin
CAS Number106685-40-9
Molecular FormulaC₂₈H₂₈O₃
Molecular Weight412.52 g/mol
CategoryTopical Retinoid / Dermatological Agent
AppearanceWhite to Off-white Powder
GradeUSP / EP

Analytical Specifications

ParameterSpecification
Assay98.0% – 102.0%
Loss on DryingNMT 1.0%
Melting PointN/A
Heavy MetalsNMT 20 ppm
pHN/A
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Packing1 kg foil pouches / as per requirement
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