Active Pharmaceutical Ingredient

Agomelatine

Also known as: Valdoxan

CAS: 138112-76-2 Antidepressant / CNS EP Standard Bulk Supply Available
Agomelatine API Manufacturer India | Mediocon Inc
Agomelatine — Pharmaceutical Grade API

Product Overview

CAS No: 138112-76-2  |  MF: C₁₅H₁₇NO₂  |  MW: 243.30 g/mol

Agomelatine is a novel antidepressant acting as a melatonin receptor agonist (MT1/MT2) and a serotonin receptor antagonist (5-HT2C). It resynchronizes circadian rhythms and improves sleep quality. Mediocon Inc supplies pharmaceutical-grade Agomelatine for licensed pharmaceutical manufacturers.

Key Features

  • Unique melatonergic antidepressant
  • EP compliant quality
  • Circadian rhythm resynchronization
  • Improved tolerability vs classical antidepressants

Applications

  • Major depressive disorder tablets
  • Circadian rhythm disorder treatment
  • Insomnia-associated depression
  • Specialty CNS formulations

Why Choose Mediocon

  • ISO 9001:2015 & GMP certified manufacturing
  • Consistent batch-to-batch quality with full CoA
  • Export-ready documentation: COO, MSDS, DMF
  • Flexible MOQ for both R&D and commercial scale
  • Dedicated QA support for regulatory filings

Product Specifications

Product NameAgomelatine
Also Known AsValdoxan
CAS Number138112-76-2
Molecular FormulaC₁₅H₁₇NO₂
Molecular Weight243.30 g/mol
CategoryAntidepressant / Melatonergic Agent
AppearanceWhite to Off-white Powder
GradeEP / In-house Standard

Analytical Specifications

ParameterSpecification
Assay98.0% – 102.0%
Loss on DryingNMT 0.5%
Melting Point95°C – 99°C
Heavy MetalsNMT 10 ppm
pHN/A
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Packing1 kg foil pouches / as per requirement
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