Active Pharmaceutical Ingredient

Amiloride

Also known as: Midamor

CAS: 2016-88-8 Potassium-Sparing Diuretic USP / BP / IP Bulk Supply Available
Amiloride API Manufacturer India | Mediocon Inc
Amiloride — Pharmaceutical Grade API

Product Overview

CAS No: 2016-88-8  |  MF: C₆H₈ClN₇O  |  MW: 229.63 g/mol

Amiloride hydrochloride is a potassium-sparing diuretic that blocks epithelial sodium channels (ENaC) in the distal nephron. It is used in the treatment of hypertension and oedema, often combined with thiazide diuretics. Mediocon Inc supplies pharmaceutical-grade Amiloride meeting USP, BP, and IP standards.

Key Features

  • Potassium-sparing ENaC blocker
  • USP/BP/IP compliant quality
  • Reduces risk of hypokalaemia in diuretic therapy
  • Widely used in combination diuretics

Applications

  • Hypertension combination tablets
  • Congestive heart failure oedema
  • Combination diuretic formulations
  • Ascites management in liver disease

Why Choose Mediocon

  • ISO 9001:2015 & GMP certified manufacturing
  • Consistent batch-to-batch quality with full CoA
  • Export-ready documentation: COO, MSDS, DMF
  • Flexible MOQ for both R&D and commercial scale
  • Dedicated QA support for regulatory filings

Product Specifications

Product NameAmiloride
Also Known AsMidamor
CAS Number2016-88-8
Molecular FormulaC₆H₈ClN₇O
Molecular Weight229.63 g/mol
CategoryPotassium-Sparing Diuretic
AppearanceYellow to Greenish-yellow Crystalline Powder
GradeUSP / BP / IP

Analytical Specifications

ParameterSpecification
Assay98.5% – 101.5%
Loss on DryingNMT 1.0%
Melting Point293°C – 296°C (decomp)
Heavy MetalsNMT 10 ppm
pH3.5 – 5.0 (1% solution)
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Packing25 kg HDPE drums / as per requirement
💬
Mediocon AI
Hello 👋 How can I help you today?