Active Pharmaceutical Ingredient

Amphotericin B

Also known as: Fungizone

CAS: 1397-89-3 Polyene Antifungal USP / BP Bulk Supply Available
Amphotericin B API Manufacturer India | Mediocon Inc
Amphotericin B — Pharmaceutical Grade API

Product Overview

CAS No: 1397-89-3  |  MF: C₄₇H₇₃NO₁₇  |  MW: 924.08 g/mol

Amphotericin B is a polyene macrolide antifungal agent produced by Streptomyces nodosus. It acts by binding to ergosterol in the fungal cell membrane causing increased permeability. Mediocon Inc supplies pharmaceutical-grade Amphotericin B meeting USP and BP standards for injectable and liposomal formulations.

Key Features

  • Broad-spectrum polyene antifungal
  • USP/BP compliant quality
  • Active against Candida, Aspergillus & Cryptococcus
  • Suitable for IV and liposomal formulations

Applications

  • Systemic fungal infection IV infusion
  • Cryptococcal meningitis treatment
  • Invasive aspergillosis management
  • Liposomal amphotericin B formulations

Why Choose Mediocon

  • ISO 9001:2015 & GMP certified manufacturing
  • Consistent batch-to-batch quality with full CoA
  • Export-ready documentation: COO, MSDS, DMF
  • Flexible MOQ for both R&D and commercial scale
  • Dedicated QA support for regulatory filings

Product Specifications

Product NameAmphotericin B
Also Known AsFungizone
CAS Number1397-89-3
Molecular FormulaC₄₇H₇₃NO₁₇
Molecular Weight924.08 g/mol
CategoryPolyene Antifungal
AppearanceYellow to Orange Powder
GradeUSP / BP

Analytical Specifications

ParameterSpecification
AssayNLT 750 mcg/mg
Loss on DryingNMT 5.0%
Melting PointN/A
Heavy MetalsNMT 30 ppm
pH6.0 – 8.0 (0.1% solution)
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Packing1 kg amber glass bottles / as per requirement
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