Active Pharmaceutical Ingredient

Chy-Max® M Manufacturer & Supplier in India | MEDIOCON INC

GMP Certified Aurangabad, Maharashtra, India
Chy-Max® M Manufacturer & Supplier in India | MEDIOCON INC — Mediocon Inc
Chy-Max® M Manufacturer & Supplier in India | MEDIOCON INC

Product Overview

Chy-Max® M – Fermentation-Produced Chymosin

MEDIOCON INC offers Chy-Max® M, a second-generation fermentation-produced chymosin (FPC) used as a highly specific milk coagulant in cheese manufacturing.

Chy-Max® M is designed to provide high milk-clotting specificity with reduced proteolytic activity. The active milk-coagulating enzyme is chymosin (EC 3.4.23.4). The product is produced by submerged fermentation on a vegetable substrate using Aspergillus niger var. awamori, which is maintained under contained conditions and is not present in the final product.

The high specificity of Chy-Max® M for κ-casein supports efficient curd formation while limiting unwanted protein breakdown. This can contribute to improved cheese yield, texture control, whey quality and reduced bitterness.

Product Overview

Chy-Max® M is a fermentation-produced dairy coagulant intended for cheese production.

Unlike traditional animal rennet, fermentation-produced chymosin is produced through a controlled fermentation process. Chy-Max® M is specifically designed to achieve a high ratio of milk-clotting activity relative to general proteolytic activity.

The product is available in liquid and granulate formats, with different strengths and volumes depending on the commercial variant and market.

Active Enzyme

Enzyme: Chymosin

EC Number: EC 3.4.23.4

Enzyme Type: Fermentation-produced chymosin

Function: Milk coagulation / cheese coagulant

Chymosin acts primarily on κ-casein in milk, initiating coagulation of the casein micelle and formation of the curd required for cheesemaking.

Production

Chy-Max® M is produced through submerged fermentation using a vegetable-based substrate with Aspergillus niger var. awamori under contained manufacturing conditions. The production organism is not present in the final product.

Key Features

  • Fermentation-produced chymosin
  • Second-generation FPC
  • High milk-clotting specificity
  • Reduced proteolytic activity
  • Efficient κ-casein coagulation
  • Suitable for cheese manufacturing
  • Supports consistent curd formation
  • Can improve cheese yield
  • Supports texture control
  • Can reduce bitterness associated with excessive proteolysis
  • Supports higher-quality whey
  • Available in different strengths
  • Available in liquid and granulate formats 

Benefits in Cheese Manufacturing

Improved Cheese Yield

The high specificity of Chy-Max® M can help retain more milk protein in the cheese matrix, supporting improved yield. Novonesis reports cheese-yield improvement of up to 1.2% for its Chy-Max® M coagulant in certain applications.

Better Texture Control

Reduced proteolytic activity helps limit excessive casein breakdown, supporting firm and stable cheese texture during storage.

Reduced Bitterness

The high specificity of the enzyme helps minimize unwanted protein breakdown that can contribute to bitterness.

Improved Whey Quality

Greater specificity can reduce unwanted protein degradation and support the recovery of higher-value whey proteins.

Process Control

Chy-Max® M is designed to provide robust coagulation performance across cheesemaking conditions, helping producers achieve more consistent processing.

Applications

Chy-Max® M is used as a coagulant in:

  • Cheese manufacturing
  • Hard cheese
  • Semi-hard cheese
  • Soft cheese
  • Pasta filata cheese
  • Cheddar-type cheese
  • Continental cheeses
  • Industrial cheesemaking
  • Dairy processing applications

Novonesis describes Chy-Max® M as suitable for multiple cheese applications.

Suitable for Vegetarian Cheese

Chy-Max® M is a fermentation-produced chymosin and is described by Novonesis/Chr. Hansen materials as suitable for vegetarians. It has also been described as Halal and Kosher certified, subject to the applicable product variant and certification.

Product Formats

Liquid

Chy-Max® M is available as a liquid coagulant in different commercial strengths.

Granulate

Granulated formats are also available depending on product variant and market.

Product Strength

Commercial Chy-Max® M products are supplied in different activity strengths.

For example, historical product information describes a 1000 IMCU/mL liquid specification with a minimum guaranteed activity of 950 IMCU/mL at best-before date. Do not use these values as the generic specification for every Chy-Max® M variant.

The exact activity should therefore be entered according to the specific product strength and current CoA.

Quality & Documentation

MEDIOCON INC can support commercial sourcing requirements with available technical and quality documentation, subject to product availability and supplier documentation.

Typical documentation may include:

  • Certificate of Analysis (CoA)
  • Product Specification
  • Technical Data Sheet
  • Safety Data Sheet (SDS)
  • Enzyme activity specification
  • Enzyme identification
  • Microbiological specification
  • Allergen Statement
  • GMO Statement
  • Vegetarian suitability documentation
  • Halal Certificate
  • Kosher Certificate
  • Food-enzyme regulatory documentation
  • Country of Origin
  • Batch documentation

Storage

Storage conditions are variant-specific and should be taken directly from the current manufacturer's product specification.

Protect the enzyme preparation from:

  • Excessive heat
  • Direct sunlight
  • Moisture
  • Contamination
  • Uncontrolled temperature exposure

Handling

Chy-Max® M is an enzyme preparation. Appropriate workplace handling procedures should be followed.

Enzyme dust or aerosols can cause sensitization in susceptible individuals, so appropriate occupational controls and personal protective equipment should be used when handling concentrated enzyme preparations.

Packaging

Packaging depends on the specific Chy-Max® M strength and format.

Commercial formats can include:

  • Liquid containers
  • Granulate containers
  • Bulk industrial packaging

Exact packaging should be confirmed according to the selected product variant.

Important Product Classification

Chy-Max® M is a food enzyme / dairy coagulant, not a pharmaceutical API.

Therefore:

  • CAS number is not the primary product identifier.
  • Molecular formula is not applicable to the commercial enzyme preparation as a whole.
  • Molecular weight is not applicable to the commercial preparation as a whole.
  • Enzyme activity, expressed in appropriate milk-clotting units, is more relevant than a conventional chemical assay.
  • Exact activity must be specified according to the particular commercial variant.

Why Choose Chy-Max® M?

Chy-Max® M combines high milk-clotting specificity with comparatively low proteolytic activity, making it suitable for cheesemakers seeking consistent coagulation, improved yield, controlled texture and good whey quality.

MEDIOCON INC supports customers seeking specialty food enzymes and dairy-processing ingredients with appropriate technical, quality and regulatory documentation.

Product Specifications

Product NameChy-Max® M Manufacturer & Supplier in India | MEDIOCON INC

Sourcing, Regulatory & Export Information

Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Chy-Max® M Manufacturer & Supplier in India | MEDIOCON INC and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.

Our Chy-Max® M Manufacturer & Supplier in India | MEDIOCON INC is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.

Export Markets

  • USA — FDA-registered facility; DMF support available for ANDA/NDA filings
  • Europe — EMA-compliant documentation; CEP/EDMF support on request
  • Africa & Middle East — WHO-GMP certified; competitive pricing for emerging markets
  • Southeast Asia — established logistics network; temperature-controlled shipments
  • India domestic — schedule H/X compliance; all state licensing documentation provided

Quality & Compliance

  • ISO 9001:2015 certified quality management system
  • GMP-certified manufacturing facility, Aurangabad, Maharashtra
  • Full batch traceability from raw material to finished API
  • Dedicated QA team for customer audits and regulatory queries

Frequently Asked Questions — Chy-Max® M Manufacturer & Supplier in India | MEDIOCON INC

What is Chy-Max® M?
Chy-Max® M is a second-generation fermentation-produced chymosin used as a milk coagulant in cheese manufacturing.
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