Active Pharmaceutical Ingredient

Esmolol API Manufacturer & Supplier in India

CAS: 81161-17-3 GMP Certified Aurangabad, Maharashtra, India

Product Overview

CAS No: 81161-17-3

Esmolol API Manufacturer, Supplier & Exporter

Premium Quality Esmolol API from India

Mediocon Inc. is a trusted manufacturer, supplier, and exporter of Esmolol Active Pharmaceutical Ingredient (API), serving pharmaceutical companies across domestic and international markets. Our Esmolol API is manufactured under stringent quality standards to ensure excellent purity, safety, and regulatory compliance.

Esmolol is an ultra-short-acting selective beta-1 adrenergic receptor blocker primarily used for rapid control of heart rate and blood pressure in emergency and perioperative settings. It is widely utilized in injectable formulations because of its rapid onset and short duration of action.

Our manufacturing process follows GMP guidelines with comprehensive quality control testing, complete documentation, and reliable export support.

Product Specifications

Product NameEsmolol API Manufacturer & Supplier in India
CAS Number81161-17-3
AppearanceWhite to Off-white Powder

Analytical Specifications

ParameterSpecification
AppearanceWhite to Off-white Powder
IdentificationIR & HPLC Complies
Assay (HPLC)98.0% – 102.0%
Loss on DryingNMT 20 ppm
Residue on IgnitionNMT 0.1%
Heavy MetalsNMT 20 ppm
pH (1% Solution)4.5 – 6.5
Individual ImpurityNMT 0.5%
Total ImpuritiesNMT 1.0%
Water ContentNMT 1.0%
Specific RotationNot Applicable
Melting PointApproximately 198–205°C (with decomposition)
SolubilityFreely soluble in water; soluble in methanol; slightly soluble in ethanol

Sourcing, Regulatory & Export Information

Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Esmolol API Manufacturer & Supplier in India (CAS 81161-17-3) and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.

Our Esmolol API Manufacturer & Supplier in India is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.

Export Markets

  • USA — FDA-registered facility; DMF support available for ANDA/NDA filings
  • Europe — EMA-compliant documentation; CEP/EDMF support on request
  • Africa & Middle East — WHO-GMP certified; competitive pricing for emerging markets
  • Southeast Asia — established logistics network; temperature-controlled shipments
  • India domestic — schedule H/X compliance; all state licensing documentation provided

Quality & Compliance

  • ISO 9001:2015 certified quality management system
  • GMP-certified manufacturing facility, Aurangabad, Maharashtra
  • Full batch traceability from raw material to finished API
  • Dedicated QA team for customer audits and regulatory queries

Frequently Asked Questions — Esmolol API Manufacturer & Supplier in India

What is Esmolol?
Esmolol is an ultra-short-acting, cardioselective beta-1 adrenergic receptor blocker primarily used for the rapid control of heart rate and blood pressure in emergency and perioperative settings. It is administered intravenously and provides fast onset and quick recovery after discontinuation.
How does Esmolol work?
Esmolol selectively blocks beta-1 adrenergic receptors in the heart, reducing heart rate, myocardial contractility, and cardiac output. This helps decrease blood pressure and oxygen demand of the heart.
What is Esmolol used for?
Esmolol is commonly used for: Supraventricular tachycardia (SVT) Rapid ventricular rate in atrial fibrillation or atrial flutter Perioperative hypertension and tachycardia Hypertensive emergencies (in selected cases) Heart rate control during surgery and critical care
Is Esmolol suitable for long-term treatment?
No. Due to its extremely short duration of action, Esmolol is intended only for short-term intravenous use in hospitals and intensive care settings.
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