Siberian Rhubarb Extract, also known as Rhapontic Rhubarb Root Extract, is a botanical ingredient obtained from the roots of Rheum rhaponticum. It is used in specialized nutraceutical and women's-health formulations, particularly products designed around menopausal and perimenopausal wellness. FDA's substance database identifies Rheum rhaponticum root and lists “Herbal Extract of the Roots of Rhapontic (Siberian) Rhubarb” among its names.
MEDIOCON INC offers Siberian/Rhapontic Rhubarb Extract for suitable health supplement, nutraceutical and women's wellness formulations, subject to the applicable product specification and regulatory requirements.
Siberian Rhubarb (Rheum rhaponticum) is a botanical species originating from Central Asia. Its roots contain naturally occurring hydroxystilbene compounds, particularly rhaponticin and desoxyrhaponticin, together with their corresponding aglycones.
Standardized Rheum rhaponticum root extracts have been clinically investigated for menopausal symptoms, including vasomotor and other climacteric complaints.
Product Name: Extract of Siberian Rhubarb
Alternative Name: Rhapontic Rhubarb Root Extract
Botanical Name: Rheum rhaponticum
Common Name: Siberian Rhubarb
Plant Part: Root
Category: Botanical Nutraceutical Ingredient
Application: Women's Health / Menopausal Wellness
Form: Dry Extract / Powder
The ingredient is obtained from the root of Rheum rhaponticum. The FDA substance record identifies Rheum rhaponticum root as a plant-derived substance and includes the synonym “Herbal Extract of the Roots of Rhapontic (Siberian) Rhubarb.”
The characteristic compounds of specialized Rheum rhaponticum root extracts include:
ERr 731, a specific standardized extract, has been described as being characterized by these hydroxystilbene compounds.
Siberian/Rhapontic Rhubarb Extract may be used in:
Clinical research on the specific ERr 731 extract has reported reductions in menopausal symptom scores and hot-flush severity in perimenopausal women.
A randomized, double-blind, placebo-controlled study involving 109 women reported that the specific ERr 731 extract significantly reduced menopausal symptom scores and hot-flush frequency and severity over 12 weeks compared with placebo.
A 2024 systematic review and meta-analysis covering four studies and 390 participants also reported a significant reduction in Menopause Rating Scale scores with ERr 731, while noting heterogeneity and the need for further research.
A 2026 study further evaluated ERr 731 in perimenopausal women over a 12-week randomized trial followed by a longer observational period, reporting sustained improvements in several climacteric complaints.
A commercially documented example of a standardized Rheum rhaponticum extract is ERr 731, where a 4 mg serving has been described as providing approximately 2.2 mg rhaponticin and 1 mg desoxyrhaponticin.
Important: Do not use these numbers as the specification for generic Siberian Rhubarb Extract unless your actual material is the same standardized extract and your CoA supports them.
MEDIOCON INC can supply Siberian/Rhapontic Rhubarb Extract according to an agreed product specification.
Quality documentation may include:
Store in a cool, dry and well-closed environment, protected from excessive heat, moisture and direct sunlight.
Exact storage conditions should follow the validated supplier/manufacturer specification.
Siberian Rhubarb Extract can be supplied in packaging suitable for the intended application and commercial quantity.
Possible formats include:
The regulatory status and permitted claims for Rheum rhaponticum extracts vary by country and by the specific extract preparation.
Claims on a finished supplement should therefore be reviewed for the target market. Do not describe generic Siberian Rhubarb Extract as ERr 731® unless the supplied ingredient is genuinely that branded extract and you have authorization to use the trademark.
| Parameter | Specification |
|---|---|
| Appearance | Brown to reddish-brown dry extract powder |
Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Extract of Siberian Rhubarb Manufacturer & Supplier in India | MEDIOCON INC and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.
Our Extract of Siberian Rhubarb Manufacturer & Supplier in India | MEDIOCON INC is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.
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