Active Pharmaceutical Ingredient

Isoproterenol Sulfate API Manufacturer and Supplier in India

CAS: 51-30-9 Active Pharmaceutical Ingredient Pharmaceutical Grade GMP Certified Aurangabad, Maharashtra, India
Isoproterenol Sulfate API Manufacturer and Supplier in India — Mediocon Inc
Isoproterenol Sulfate API Manufacturer and Supplier in India

Product Overview

CAS No: 51-30-9 | Grade: Pharmaceutical Grade | Category: Active Pharmaceutical Ingredient

MEDIOCON INC – Isoproterenol Sulfate is the sulfate salt of Isoproterenol, a synthetic non-selective β-adrenergic receptor agonist used as a cardiovascular pharmaceutical active ingredient. It produces positive chronotropic and inotropic effects and has applications in specific cardiac and cardiovascular settings.

Isoproterenol Sulfate API

Isoproterenol Sulfate is a sympathomimetic pharmaceutical compound belonging to the catecholamine class. It stimulates β₁- and β₂-adrenergic receptors, increasing cardiac rate and contractility while also producing relaxation of bronchial and certain vascular smooth muscles.

The compound has historically been used in pharmaceutical formulations and cardiovascular medicine, including management of certain types of bradycardia and heart block, depending on the applicable clinical setting and regulatory authorization.

Chemical Information

Product Name: Isoproterenol Sulfate
CAS Number: 51-30-9
Molecular Formula: C₁₁H₁₇NO₆S
Molecular Weight: 291.32 g/mol
Chemical Class: Catecholamine / Phenylethanolamine Derivative
Pharmacological Class: Non-selective β-Adrenergic Agonist
Salt Form: Sulfate
Parent Compound: Isoproterenol
Parent CAS Number: 7683-59-2
IUPAC Name: 4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol sulfate
Synonyms: Isoproterenol Sulfate, Isoprenaline Sulfate, Isoproterenol Sulfate Hemihydrate

Mechanism of Action

Isoproterenol is a non-selective β-adrenergic receptor agonist.

It stimulates:

  • β₁ receptors in the heart, increasing heart rate and myocardial contractility.
  • β₂ receptors in smooth muscle, contributing to bronchodilation and vasodilation.

Through these actions, Isoproterenol can increase cardiac output while reducing certain forms of peripheral vascular resistance.

Manufacturing and Quality

MEDIOCON INC focuses on supplying pharmaceutical active ingredients with emphasis on quality, consistency, technical documentation and reliable supply.

Isoproterenol Sulfate quality evaluation may include:

  • Identification
  • Assay by HPLC
  • Related substances
  • Catecholamine-related impurities
  • Residual solvents
  • Loss on drying
  • Residue on ignition
  • Heavy metals
  • Water content
  • pH
  • Optical purity
  • Sulfate content
  • Other product-specific analytical parameters

The exact acceptance criteria should be confirmed against the applicable approved specification and batch-specific Certificate of Analysis.

Applications

Isoproterenol Sulfate may be used in:

  • Cardiovascular pharmaceutical formulations
  • Management of certain bradyarrhythmias
  • Temporary treatment of certain heart block conditions
  • Cardiac electrophysiology research
  • β-adrenergic receptor research
  • Cardiovascular pharmacology
  • Pharmaceutical research and development

Approved indications and clinical applications vary according to country and regulatory labeling.

Product Characteristics

Isoproterenol Sulfate is generally described as a white to almost white crystalline powder.

Appearance: White to almost white crystalline powder

The exact commercial appearance specification should be confirmed against the applicable MEDIOCON INC product specification and batch COA.

Storage

Because catecholamine compounds can be susceptible to oxidation and light exposure, appropriate protective packaging and storage conditions are important.

The exact storage requirements should follow the applicable product specification, stability data and validated storage conditions.

Packaging and Documentation

Product availability, packaging configuration, Certificate of Analysis (COA), Safety Data Sheet (SDS/MSDS), technical specifications and analytical documentation should be confirmed with MEDIOCON INC according to customer requirements and applicable regulatory standards.

Product Specifications

Product NameIsoproterenol Sulfate API Manufacturer and Supplier in India
CAS Number51-30-9
CategoryActive Pharmaceutical Ingredient
GradePharmaceutical Grade
AppearanceWhite to almost white crystalline powder
StandardsPharmaceutical Specifications

Analytical Specifications

ParameterSpecification
AppearanceWhite to almost white crystalline powder

Sourcing, Regulatory & Export Information

Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Isoproterenol Sulfate API Manufacturer and Supplier in India (CAS 51-30-9) and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.

Our Isoproterenol Sulfate API Manufacturer and Supplier in India is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.

Export Markets

  • USA — FDA-registered facility; DMF support available for ANDA/NDA filings
  • Europe — EMA-compliant documentation; CEP/EDMF support on request
  • Africa & Middle East — WHO-GMP certified; competitive pricing for emerging markets
  • Southeast Asia — established logistics network; temperature-controlled shipments
  • India domestic — schedule H/X compliance; all state licensing documentation provided

Quality & Compliance

  • ISO 9001:2015 certified quality management system
  • GMP-certified manufacturing facility, Aurangabad, Maharashtra
  • Full batch traceability from raw material to finished API
  • Dedicated QA team for customer audits and regulatory queries

Frequently Asked Questions — Isoproterenol Sulfate API Manufacturer and Supplier in India

What is Isoproterenol Sulfate?
Isoproterenol Sulfate is the sulfate salt of Isoproterenol, a synthetic non-selective β-adrenergic receptor agonist.
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