MEDIOCON INC – Isradipine is a dihydropyridine calcium channel blocker used as an antihypertensive pharmaceutical active ingredient. It selectively inhibits L-type calcium channels in vascular smooth muscle, producing vasodilation and reducing peripheral vascular resistance.
Isradipine is a synthetic dihydropyridine derivative belonging to the calcium channel blocker class. Its primary pharmacological effect is relaxation of vascular smooth muscle, which results in decreased systemic vascular resistance and lowering of blood pressure.
Isradipine has been used in pharmaceutical formulations for the management of hypertension and has also been investigated in cardiovascular pharmacology.
Product Name: Isradipine
CAS Number: 75695-93-1
Molecular Formula: C₁₉H₂₁N₃O₆
Molecular Weight: 387.39 g/mol
Chemical Class: Dihydropyridine Derivative
Therapeutic Class: Calcium Channel Blocker / Antihypertensive
IUPAC Name: 4-(4-benzofurazan-5-yl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid 3-methyl 5-(1-methylethyl) ester
Synonyms: Isradipine, Isradipinum
Development Code: PN 200-110
Isradipine selectively blocks L-type calcium channels in vascular smooth muscle.
Reduced calcium influx decreases vascular smooth-muscle contraction and produces arteriolar vasodilation. This lowers peripheral vascular resistance and consequently reduces blood pressure.
Compared with its vascular effects, Isradipine has relatively limited direct effects on cardiac contractility at therapeutic concentrations.
MEDIOCON INC focuses on supplying pharmaceutical active ingredients with emphasis on quality, consistency, technical documentation and reliable supply.
Isradipine quality evaluation may include:
The exact acceptance criteria should be confirmed against the applicable approved specification and batch-specific Certificate of Analysis.
Isradipine may be used in:
Approved indications and formulation uses depend on the regulatory jurisdiction and applicable product labeling.
Isradipine is generally described as a yellow to pale yellow crystalline powder.
Appearance: Yellow to pale yellow crystalline powder
The exact commercial appearance specification should be confirmed against the applicable MEDIOCON INC product specification and batch COA.
Product availability, packaging configuration, Certificate of Analysis (COA), Safety Data Sheet (SDS/MSDS), technical specifications and analytical documentation should be confirmed with MEDIOCON INC according to customer requirements and applicable regulatory standards.
| Parameter | Specification |
|---|---|
| Appearance | Yellow to pale yellow crystalline powder |
Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Isradipine API Manufacturer and Supplier in India (CAS 75695-93-1) and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.
Our Isradipine API Manufacturer and Supplier in India is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.
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