MEDIOCON INC – Ketanserin is a synthetic serotonin receptor antagonist, primarily recognized for its selective activity at the 5-HT₂A receptor. It has been extensively studied in cardiovascular pharmacology, vascular biology, platelet research and serotonin-receptor pharmacology.
Ketanserin is a member of the arylpiperidine class of serotonin receptor antagonists. It selectively blocks serotonin-mediated activity at 5-HT₂ receptors, with particularly strong affinity for the 5-HT₂A receptor subtype.
Ketanserin has been used extensively as a pharmacological research tool for investigating serotonin-mediated vascular responses, platelet aggregation and receptor signaling.
Product Name: Ketanserin
CAS Number: 74050-98-9
Molecular Formula: C₂₂H₂₂FN₃O₃
Molecular Weight: 395.43 g/mol
Chemical Class: Aryl Piperidine / Serotonin Receptor Antagonist
Pharmacological Class: 5-HT₂A Receptor Antagonist
IUPAC Name: 3-[2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl]-2,4(1H,3H)-quinazolinedione
Synonyms: Ketanserin, Ketanserinum
Parent Research Class: Serotonin receptor antagonist
Ketanserin acts primarily as an antagonist at 5-HT₂A serotonin receptors. By blocking serotonin binding to these receptors, it can inhibit serotonin-mediated smooth-muscle contraction and other downstream physiological responses.
Ketanserin has also been used as a research tool to distinguish 5-HT₂A-mediated responses from responses mediated through other serotonin receptor subtypes.
MEDIOCON INC focuses on supplying pharmaceutical and specialty chemical ingredients with emphasis on quality, consistency, technical documentation and reliable supply.
Ketanserin quality evaluation may include:
The exact analytical acceptance criteria should be confirmed against the current approved specification and batch-specific Certificate of Analysis.
Ketanserin may be used for:
Ketanserin is generally described as a crystalline solid in chemical reference information.
Appearance: White to off-white crystalline solid/powder
The exact commercial appearance specification should be confirmed against the applicable MEDIOCON INC product specification and batch COA.
Ketanserin is also available as Ketanserin Tartrate, which is a distinct salt form and should be maintained as a separate product record.
Ketanserin: CAS 74050-98-9
Ketanserin Tartrate: CAS 83851-91-4
The free base and tartrate salt have different molecular formulas and molecular weights and should not be treated as interchangeable specifications.
Product availability, packaging configuration, Certificate of Analysis (COA), Safety Data Sheet (SDS/MSDS), technical specifications and analytical documentation should be confirmed with MEDIOCON INC according to the intended application.
| Parameter | Specification |
|---|---|
| Appearance | White to off-white crystalline solid/powder |
Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Ketanserin API Manufacturer and Supplier in India (CAS 74050-98-9) and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.
Our Ketanserin API Manufacturer and Supplier in India is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.
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