MEDIOCON INC – Labetalol Hydrochloride is an adrenergic receptor-blocking pharmaceutical active ingredient with both selective α1-adrenergic blocking and non-selective β-adrenergic blocking activity. It is primarily used as an antihypertensive agent for the management of high blood pressure. Labetalol Hydrochloride has the molecular formula C₁₉H₂₄N₂O₃·HCl and molecular weight 364.87 g/mol.
Labetalol Hydrochloride is the hydrochloride salt of Labetalol and belongs to the adrenergic receptor antagonist class. Its combined α1- and β-adrenergic blocking activity produces vasodilation while also reducing cardiac sympathetic activity.
Labetalol Hydrochloride is identified by CAS Number 32780-64-6.
Product Name: Labetalol Hydrochloride
CAS Number: 32780-64-6
Molecular Formula: C₁₉H₂₄N₂O₃·HCl
Molecular Weight: 364.87 g/mol
Chemical Class: Adrenergic receptor antagonist
Therapeutic Class: Antihypertensive / Alpha- and Beta-adrenergic blocker
Parent Compound: Labetalol
Parent CAS Number: 36894-69-6
PubChem CID: 71412
Labetalol Hydrochloride has two asymmetric centers and is present as a molecular complex of two diastereoisomeric pairs; the R,R' stereoisomer, dilevalol, represents approximately 25% of racemic labetalol.
Labetalol Hydrochloride combines competitive α1-adrenergic receptor blockade with non-selective competitive β-adrenergic receptor blockade.
α1-receptor blockade reduces peripheral vascular resistance through vasodilation, while β-receptor blockade decreases sympathetic cardiac activity. Together, these effects contribute to reductions in blood pressure and heart rate.
MEDIOCON INC focuses on supplying pharmaceutical and specialty chemical ingredients with emphasis on quality, consistency, technical documentation and reliable supply.
Labetalol Hydrochloride quality evaluation may include identification, assay, chromatographic purity, related substances, residual solvents, water content, residue on ignition and other parameters according to the applicable product specification.
The exact analytical acceptance criteria should be confirmed against the current approved specification and batch-specific Certificate of Analysis.
Labetalol Hydrochloride is used as an antihypertensive pharmaceutical ingredient. It is formulated for oral administration and is also used in injectable formulations for appropriate clinical settings.
The exact indication, dosage form and regulatory requirements should be confirmed according to the applicable market authorization and current prescribing information.
Official drug labeling describes Labetalol Hydrochloride as a white to off-white crystalline powder. Depending on the referenced specification, it may be described as soluble or sparingly soluble in water; therefore, the exact solubility statement should be matched to the applicable pharmacopoeial specification.
Appearance: White to off-white crystalline powder
Product availability, packaging configuration, Certificate of Analysis (COA), Safety Data Sheet (SDS/MSDS), technical specifications and other documentation should be confirmed with MEDIOCON INC according to the intended application and customer requirements.
| Parameter | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Labetalol Hydrochloride API Manufacturer and Supplier in India (CAS 32780-64-6) and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.
Our Labetalol Hydrochloride API Manufacturer and Supplier in India is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.
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