MEDIOCON INC – Ledoxantrone, also known as CI-958, is a synthetic bioactive compound belonging to the substituted benzothiopyranoindazole class. It has been investigated for antineoplastic activity and is reported to interfere with DNA/RNA synthesis-related processes.
Ledoxantrone is a research-stage antineoplastic compound with reported DNA-intercalating and DNA helicase inhibitory activity. Research has investigated Ledoxantrone and related compounds for their potential effects on cancer-cell proliferation and nucleic-acid synthesis.
Product Name: Ledoxantrone
CAS Number: 113457-05-9
Molecular Formula: C₂₁H₂₇N₅OS
Molecular Weight: Approximately 397.54 g/mol
Chemical Class: Substituted benzothiopyranoindazole / antineoplastic compound
Synonyms: CI-958, CI 958, Ledoxantrone
InChIKey: IMMFHFBXRWAZGX-UHFFFAOYSA-N
Ledoxantrone (CI-958) has been reported as an inhibitor of DNA helicases, with research describing inhibition of DNA/RNA synthesis-related processes. One published study investigated CI-958 as a new antitumor intercalator, while later research reported DNA helicase inhibitory activity.
MEDIOCON INC focuses on supplying pharmaceutical and specialty chemical ingredients with emphasis on quality, consistency, technical documentation and dependable supply.
For Ledoxantrone, quality evaluation may include identity, assay, chromatographic purity, related substances, residual solvents, water content, residue on ignition and other parameters according to the applicable product specification.
The exact analytical acceptance criteria should be confirmed against the current approved specification and batch-specific Certificate of Analysis.
Ledoxantrone has primarily been investigated as a research compound with potential antineoplastic activity. Research has examined its interaction with DNA and inhibition of DNA helicase-related processes, including investigations related to prostate cancer.
Ledoxantrone should not be represented as an approved therapeutic product unless such regulatory approval is specifically established for the intended market and formulation.
Ledoxantrone is a defined small-molecule organic compound with molecular formula C₂₁H₂₇N₅OS and molecular weight approximately 397.54 g/mol. The compound is identified by CAS 113457-05-9 and is also known as CI-958.
Product availability, packaging configuration, Certificate of Analysis (COA), Safety Data Sheet (SDS/MSDS), technical specifications and other documentation should be confirmed with MEDIOCON INC according to the intended application and customer requirements.
Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Ledoxantrone API Manufacturer and Supplier in India (CAS 113457-05-9) and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.
Our Ledoxantrone API Manufacturer and Supplier in India is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.
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