Lercanidipine API is a highly lipophilic, long-acting 1,4-dihydropyridine calcium-channel blocker used in pharmaceutical formulations for the management of hypertension. It acts primarily by inhibiting L-type calcium channels in vascular smooth muscle, reducing calcium influx and promoting relaxation of arterial smooth muscle. This vasodilatory effect decreases peripheral vascular resistance and contributes to the reduction of elevated blood pressure.
Lercanidipine is characterized by its high lipophilicity and vascular selectivity, properties that contribute to its prolonged pharmacological activity. As a dihydropyridine calcium-channel blocker, its principal cardiovascular effect is arterial vasodilation rather than direct suppression of cardiac conduction.
Chemically, Lercanidipine has the molecular formula C₃₆H₄₁N₂O₆ and a molecular weight of approximately 613.74 g/mol. It is a stereochemically defined compound containing multiple stereogenic centers. Lercanidipine is commonly supplied in pharmaceutical products as its hydrochloride salt, Lercanidipine Hydrochloride.
Lercanidipine is primarily associated with antihypertensive and cardiovascular pharmaceutical development. Its high lipophilicity allows it to interact extensively with vascular cell membranes and contributes to its long duration of action. The compound is generally incorporated into oral pharmaceutical formulations according to the applicable formulation and regulatory requirements.
MEDIOCON INC supplies Lercanidipine for applicable pharmaceutical manufacturing, formulation development, analytical research, quality-control testing and bulk API requirements, subject to product availability, applicable regulatory requirements and batch-specific documentation.
| Parameter | Specification |
|---|---|
| Appearance | Yellow crystalline powder |
Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Lercanidipine API Manufacturer & Supplier in India | MEDIOCON INC (CAS 100427-26-7) and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.
Our Lercanidipine API Manufacturer & Supplier in India | MEDIOCON INC is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.
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