Lestaurtinib API is an orally bioavailable indolocarbazole derivative and investigational multi-targeted tyrosine kinase inhibitor. It is also known by the development codes CEP-701 and KT-5555. Lestaurtinib has been studied primarily for its ability to inhibit FMS-like tyrosine kinase 3 (FLT3) and other signaling kinases involved in cellular proliferation and survival.
Lestaurtinib has demonstrated inhibitory activity against FLT3, including mutant forms associated with acute myeloid leukemia (AML). By inhibiting FLT3 signaling, it can interfere with downstream cellular pathways involved in proliferation and survival and has consequently been investigated as a targeted anticancer research compound. It has also been reported to interact with other kinase targets, including Trk and JAK2, making it a multi-target kinase research compound.
Chemically, Lestaurtinib has the molecular formula C₂₆H₂₁N₃O₄ and a molecular weight of approximately 439.46 g/mol. Its primary CAS Registry Number is 111358-88-4. It is an indolocarbazole compound with defined stereochemistry.
Lestaurtinib has been investigated in oncology and drug-development research, particularly in connection with FLT3-positive AML and kinase-mediated cellular signaling. It should be presented as an investigational/research compound, rather than as an approved therapeutic API, unless the applicable regulatory status has been independently verified.
MEDIOCON INC supplies Lestaurtinib for applicable pharmaceutical research, medicinal chemistry, drug-discovery programs, analytical studies and other legitimate scientific requirements, subject to product availability, applicable regulatory requirements and batch-specific documentation.
Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Lestaurtinib API Manufacturer & Supplier in India | MEDIOCON INC (CAS 111358-88-4) and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.
Our Lestaurtinib API Manufacturer & Supplier in India | MEDIOCON INC is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.
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