Levosulpiride API is the optically active S-enantiomer of sulpiride, belonging to the substituted benzamide class of pharmaceutical compounds. It is a selective dopamine D2/D3 receptor antagonist and is pharmacologically associated with both central dopaminergic activity and peripheral gastrointestinal effects. Levosulpiride has been used in pharmaceutical formulations for applications involving gastrointestinal motility and, in certain markets, psychiatric disorders.
Chemically, Levosulpiride is identified as N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-methoxy-5-sulfamoylbenzamide. It has the molecular formula C₁₅H₂₃N₃O₄S, molecular weight approximately 341.4 g/mol, and CAS number 23672-07-3.
The stereochemical configuration is an important characteristic of Levosulpiride because it represents the S-enantiomer of sulpiride. Its pharmacological activity is associated primarily with antagonism of dopamine D2-like receptors. PubChem identifies Levosulpiride as having roles as a dopaminergic antagonist, antiemetic and antipsychotic agent.
In pharmaceutical research and formulation development, Levosulpiride may be evaluated for gastrointestinal motility, nausea and vomiting, functional dyspepsia, reflux-related disorders and dopaminergic receptor research, depending on the intended regulatory application.
MEDIOCON INC supplies Levosulpiride for applicable pharmaceutical manufacturing, formulation development, analytical research, quality-control testing and bulk API requirements, subject to product availability and applicable regulatory documentation.
| Parameter | Specification |
|---|---|
| Appearance | White or almost white crystalline powder |
| Assay (HPLC) | 98.0% – 102.0% |
| Loss on Drying | NMT 0.5% |
| Residue on Ignition | NMT 0.1% |
| Heavy Metals | NMT 10 ppm |
| pH (1% Solution) | 8.0 – 10.0 |
| Individual Impurity | NMT 0.5% |
| Total Impurities | NMT 1.0% |
| Specific Rotation | −65° to −70° |
| Melting Point | 184°C – 189°C |
Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Levosulpiride API Manufacturer & Supplier in India | MEDIOCON INC (CAS 23672-07-3) and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.
Our Levosulpiride API Manufacturer & Supplier in India | MEDIOCON INC is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.
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