Lisofylline API is a synthetic small-molecule compound belonging to the methylxanthine derivative class and has been investigated for its anti-inflammatory and immunomodulatory properties. Lisofylline is structurally related to pentoxifylline and is characterized chemically as a hydroxyhexyl-substituted dimethylxanthine. The compound has been studied extensively in pharmaceutical research because of its potential effects on inflammatory signaling, lipid metabolism and immune-cell responses.
The chemically defined (R)-Lisofylline is identified as 1-[(5R)-5-hydroxyhexyl]-3,7-dimethylpurine-2,6-dione. It has the molecular formula C₁₃H₂₀N₄O₃, molecular weight 280.32 g/mol, and CAS No. 100324-81-0. PubChem identifies (R)-Lisofylline as a synthetic small molecule investigated for type 1 diabetes mellitus and describes it as having immunomodulatory and anti-inflammatory roles.
Lisofylline is also described as a metabolite of pentoxifylline and has been investigated in research involving inflammatory and immune-mediated processes. Its activity has attracted interest in areas including type 1 diabetes research, inflammatory disease research, immunomodulation, cellular signaling and pharmaceutical drug discovery.
An important consideration for pharmaceutical and analytical applications is the stereochemical identity of Lisofylline. The (R)- and (S)-enantiomers have different CAS numbers: (R)-Lisofylline is CAS 100324-81-0, while (S)-Lisofylline is CAS 100324-80-9. A racemic (+/−)-Lisofylline is separately identified as CAS 6493-06-7. Therefore, stereochemical identity should be confirmed before assigning a specification, COA or product listing.
MEDIOCON INC supplies Lisofylline for pharmaceutical research, analytical applications, medicinal chemistry, formulation-development programs and applicable research/API requirements, subject to product availability, applicable specifications, regulatory requirements and supporting documentation. The exact stereochemical form, grade, assay, impurity profile, packaging and Certificate of Analysis should be confirmed for the specific batch before use.
Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Lisofylline API Manufacturer & Supplier in India | MEDIOCON INC (CAS 100324-81-0) and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.
Our Lisofylline API Manufacturer & Supplier in India | MEDIOCON INC is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.
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