Active Pharmaceutical Ingredient

Lomerizine Hydrochloride API Manufacturer & Supplier in India | MEDIOCON INC

CAS: 101477-54-7 Active Pharmaceutical Ingredient Pharmaceutical Grade GMP Certified Aurangabad, Maharashtra, India
Lomerizine Hydrochloride API Manufacturer & Supplier in India | MEDIOCON INC — Mediocon Inc
Lomerizine Hydrochloride API Manufacturer & Supplier in India | MEDIOCON INC

Product Overview

CAS No: 101477-54-7 | Grade: Pharmaceutical Grade | Category: Active Pharmaceutical Ingredient

Lomerizine Hydrochloride is a pharmaceutical active ingredient belonging to the diphenylpiperazine class of compounds and is recognized for its calcium-channel blocking activity. It has been extensively investigated for its effects on voltage-dependent calcium channels, including L-type and T-type calcium channels, which are involved in calcium influx in vascular smooth muscle and neuronal cells. Through modulation of calcium ion entry, Lomerizine is associated with effects on vascular tone and neuronal excitability and has consequently been studied in the field of cerebrovascular pharmacology and migraine-related research.

Lomerizine Hydrochloride is primarily associated with pharmaceutical applications involving the development and manufacture of formulations intended for migraine-related therapy and cerebrovascular research. Its pharmacological profile has also made it a useful compound for studying calcium-channel activity, vascular responses, neuronal signaling, and mechanisms associated with cerebral blood flow. The API can be utilized in pharmaceutical formulation development, analytical testing, research and development programs, and other applications where a controlled-quality Lomerizine Hydrochloride active ingredient is required.

MEDIOCON INC supplies Lomerizine Hydrochloride for pharmaceutical, formulation-development, analytical, and research applications, subject to applicable product specifications, quality requirements, regulatory documentation, and product availability. The company focuses on providing pharmaceutical ingredients suitable for professional sourcing and development requirements, with documentation and quality information available according to the applicable product grade and supply specification.

Lomerizine Hydrochloride is commonly identified as Lomerizine Dihydrochloride, particularly for material associated with CAS No. 101477-54-7. This form has the molecular formula C₂₇H₃₀F₂N₂O₃·2HCl and a molecular weight of approximately 541.47 g/mol. It is generally described as a white to almost white crystalline powder. Because different salt forms of Lomerizine can have different CAS numbers, molecular weights, and specifications, the exact chemical form should be confirmed against the applicable certificate of analysis and product documentation before use in formulation or regulatory applications.

From a pharmaceutical-development perspective, Lomerizine Hydrochloride may be considered for API sourcing, formulation research, analytical method development, pharmaceutical research, reference-standard applications, and bulk active ingredient requirements. Appropriate handling, storage, testing, and quality-control procedures should be followed according to the manufacturer's specification and applicable regulatory requirements.

MEDIOCON INC provides Lomerizine Hydrochloride with a focus on consistent product quality, technical documentation, and reliable pharmaceutical API supply for customers involved in formulation development, research, manufacturing, and international sourcing. Buyers should verify the required grade, salt form, assay, impurity profile, analytical specifications, packaging requirements, and regulatory documentation before placing commercial orders.

Product Specifications

Product NameLomerizine Hydrochloride API Manufacturer & Supplier in India | MEDIOCON INC
CAS Number101477-54-7
CategoryActive Pharmaceutical Ingredient
GradePharmaceutical Grade
AppearanceWhite or almost white crystalline powder
StandardsPharmaceutical Specifications

Analytical Specifications

ParameterSpecification
AppearanceWhite or almost white crystalline powder
Assay (HPLC)≥98.0%
Loss on DryingNMT 1.0%
Residue on IgnitionNMT 1.0%
Heavy MetalsNMT 20 ppm
Total ImpuritiesNMT 1.0%
Melting Point214–218°C

Sourcing, Regulatory & Export Information

Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Lomerizine Hydrochloride API Manufacturer & Supplier in India | MEDIOCON INC (CAS 101477-54-7) and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.

Our Lomerizine Hydrochloride API Manufacturer & Supplier in India | MEDIOCON INC is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.

Export Markets

  • USA — FDA-registered facility; DMF support available for ANDA/NDA filings
  • Europe — EMA-compliant documentation; CEP/EDMF support on request
  • Africa & Middle East — WHO-GMP certified; competitive pricing for emerging markets
  • Southeast Asia — established logistics network; temperature-controlled shipments
  • India domestic — schedule H/X compliance; all state licensing documentation provided

Quality & Compliance

  • ISO 9001:2015 certified quality management system
  • GMP-certified manufacturing facility, Aurangabad, Maharashtra
  • Full batch traceability from raw material to finished API
  • Dedicated QA team for customer audits and regulatory queries

Frequently Asked Questions — Lomerizine Hydrochloride API Manufacturer & Supplier in India | MEDIOCON INC

What is Lomerizine Hydrochloride API?
Lomerizine Hydrochloride is a diphenylpiperazine calcium-channel blocker used in pharmaceutical applications and migraine-related research.
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