Active Pharmaceutical Ingredient

Methysergide Maleate API Manufacturer & Supplier in India | MEDIOCON INC

CAS: 129-49-7 Active Pharmaceutical Ingredient Pharmaceutical Grade GMP Certified Aurangabad, Maharashtra, India
Methysergide Maleate API Manufacturer & Supplier in India | MEDIOCON INC — Mediocon Inc
Methysergide Maleate API Manufacturer & Supplier in India | MEDIOCON INC

Product Overview

CAS No: 129-49-7 | Grade: Pharmaceutical Grade | Category: Active Pharmaceutical Ingredient

Methysergide Maleate API Manufacturer & Supplier in India

MEDIOCON INC is a trusted global manufacturer and supplier of Methysergide Maleate API in India, offering pharmaceutical and research-grade active pharmaceutical ingredients for pharmaceutical research, formulation development, analytical testing, quality control, medicinal chemistry, and related pharmaceutical applications.

Methysergide Maleate is an ergoline alkaloid and serotonin antagonist. Methysergide is the active moiety and is pharmacologically associated with antagonism of serotonin-mediated effects in vascular and gastrointestinal smooth muscle. Historically, methysergide maleate was used for the prophylaxis of migraine and other vascular headaches and for certain serotonin-related conditions.

Methysergide Maleate has the molecular formula C₂₅H₃₁N₃O₆, molecular weight 469.5 g/mol, and CAS Number 129-49-7. PubChem identifies Methysergide Maleate as an ergoline alkaloid and lists Methysergide Hydrogen Maleate, NSC-759143, and 2U7H1466GH among its identifiers.

MEDIOCON INC supplies Methysergide Maleate to pharmaceutical manufacturers, contract research organizations (CROs), biotechnology companies, universities, research institutes, analytical laboratories, and other qualified industry users, supported with applicable COA, MSDS/SDS, technical data sheets, analytical documentation, and product specifications.

Product Specifications

Product NameMethysergide Maleate API Manufacturer & Supplier in India | MEDIOCON INC
CAS Number129-49-7
CategoryActive Pharmaceutical Ingredient
GradePharmaceutical Grade
AppearanceWhite to Off-White Solid / Crystalline Powder
StandardsPharmaceutical Specifications

Analytical Specifications

ParameterSpecification
AppearanceWhite to Off-White Solid / Crystalline Powder
IdentificationIR / HPLC / LC-MS Complies
Assay (HPLC)NLT 98.0%
Loss on DryingNMT 2.0%
Residue on IgnitionNMT 1.0%
Heavy MetalsNMT 20 ppm
Individual ImpurityNMT 0.5%
Total ImpuritiesNMT 1.0%
Water ContentNMT 2.0%
Melting Point220°C – 225°C
SolubilitySoluble in water and polar organic solvents; solubility depends on the salt and solvent system

Sourcing, Regulatory & Export Information

Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Methysergide Maleate API Manufacturer & Supplier in India | MEDIOCON INC (CAS 129-49-7) and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.

Our Methysergide Maleate API Manufacturer & Supplier in India | MEDIOCON INC is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.

Export Markets

  • USA — FDA-registered facility; DMF support available for ANDA/NDA filings
  • Europe — EMA-compliant documentation; CEP/EDMF support on request
  • Africa & Middle East — WHO-GMP certified; competitive pricing for emerging markets
  • Southeast Asia — established logistics network; temperature-controlled shipments
  • India domestic — schedule H/X compliance; all state licensing documentation provided

Quality & Compliance

  • ISO 9001:2015 certified quality management system
  • GMP-certified manufacturing facility, Aurangabad, Maharashtra
  • Full batch traceability from raw material to finished API
  • Dedicated QA team for customer audits and regulatory queries

Frequently Asked Questions — Methysergide Maleate API Manufacturer & Supplier in India | MEDIOCON INC

What is Methysergide Maleate API?
Methysergide Maleate is an ergoline alkaloid salt containing methysergide as its active moiety. It has serotonin-antagonist activity and has been used historically in the prevention of vascular headaches and migraine.
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