MEDIOCON INC is a trusted global manufacturer and supplier of Metoclopramide Hydrochloride API in India, offering high-quality pharmaceutical-grade active pharmaceutical ingredients for pharmaceutical manufacturing, formulation development, analytical testing, quality control, stability studies, and research applications. Our APIs are supplied with appropriate quality documentation to support pharmaceutical development and manufacturing requirements.
Metoclopramide Hydrochloride is a dopamine-2 (D2) receptor antagonist and gastrointestinal prokinetic active pharmaceutical ingredient. It increases the tone and amplitude of gastric contractions, relaxes the pyloric sphincter and duodenal bulb, and increases intestinal peristalsis, thereby accelerating gastric emptying and intestinal transit. It is used in pharmaceutical formulations for conditions including diabetic gastroparesis and symptomatic gastroesophageal reflux disease (GERD).
Metoclopramide Hydrochloride is commonly supplied as metoclopramide monohydrochloride monohydrate. It is chemically identified as 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide monohydrochloride monohydrate. The molecular formula is C₁₄H₂₂ClN₃O₂·HCl·H₂O and the molecular weight is approximately 354.3 g/mol. It is described as a white or almost white crystalline powder that is freely soluble in water.
MEDIOCON INC supplies premium-quality Metoclopramide Hydrochloride API to pharmaceutical manufacturers, contract manufacturing organizations (CMOs), contract research organizations (CROs), formulation companies, biotechnology companies, universities, research institutes, and analytical laboratories worldwide, supported with comprehensive documentation including COA, MSDS/SDS, technical data sheets, product specifications, analytical documentation, and applicable quality documents.
| Parameter | Specification |
|---|---|
| Appearance | White or Almost White Crystalline Powder |
| Identification | IR / HPLC / Chloride Complies |
| Assay (HPLC) | 98.0% – 102.0% |
| Loss on Drying | NMT 1.0% |
| Residue on Ignition | NMT 0.5% |
| Heavy Metals | NMT 0.5% |
| Individual Impurity | NMT 0.5% |
| Total Impurities | NMT 1.0% |
| Water Content | NMT 5.0% |
| Melting Point | 182°C – 185°C |
| Solubility | Freely soluble in water; freely soluble in alcohol; sparingly soluble in chloroform; practically insoluble in ether |
Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Metoclopramide Hydrochloride API Manufacturer & Supplier in India | MEDIOCON INC (CAS 723-94-0) and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.
Our Metoclopramide Hydrochloride API Manufacturer & Supplier in India | MEDIOCON INC is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.
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