Milk Thistle Extract is a botanical ingredient derived from Silybum marianum, a flowering plant belonging to the Asteraceae family. Native to the Mediterranean region and cultivated in various parts of the world, milk thistle is recognised for its distinctive purple flowers and spiny leaves.
Milk thistle seeds are an important source of silymarin, a mixture of flavonolignans that includes silybin, isosilybin, silychristin and silydianin. The concentration of these constituents depends on the raw material, extraction process and standardisation of the final ingredient.
Milk Thistle Extract is used in botanical ingredient development and is of interest to manufacturers working with herbal formulations and nutraceutical products. Its suitability for a particular application depends on the product grade, composition and applicable regulatory requirements.
Silymarin is a mixture of naturally occurring flavonolignans associated with milk thistle fruits. It is commonly used as a marker for standardising certain milk thistle extract grades.
Silybin, also known as silibinin, is one of the principal flavonolignans in silymarin. Its content may be specified separately in certain standardised extracts.
Isosilybin is another flavonolignan associated with milk thistle and may be included in analytical profiles of standardised extracts.
These are additional constituents found in silymarin-containing milk thistle materials. Their relative concentrations vary with the source material and extraction process.
The actual constituent profile and percentages should be confirmed through the product specification and batch-specific Certificate of Analysis (CoA).
Suitable milk thistle extract grades may be evaluated for use in nutraceutical and dietary supplement formulations, subject to applicable regulations.
Milk thistle is a recognised botanical ingredient in herbal product development. The appropriate grade depends on the intended use and documented composition.
Milk thistle extracts may be evaluated in research and product development involving botanical composition, standardisation and formulation characteristics.
Manufacturers may assess standardised milk thistle extracts for incorporation into appropriate supplement formats, provided the material meets the relevant quality and regulatory requirements.
When evaluating Milk Thistle Extract, review the following information where applicable:
Analytical values and acceptance limits should be taken from the exact product specification and batch-specific CoA.
Store Milk Thistle Extract according to the approved product instructions. Keep it in its original, properly sealed packaging and protect it from moisture, excessive heat, light and other unsuitable environmental conditions. Follow the applicable safety data sheet and handling recommendations.
For Milk Thistle Extract (Silybum marianum), consult the product specification to confirm the available grade, silymarin standardisation, extraction method, packaging and intended application. Contact Mediocon for product information and enquiries.
| Parameter | Specification |
|---|---|
| Identification | Silybum marianum |
Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Milk Thistle Extract (Silybum Marianum) Manufacturer in India and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.
Our Milk Thistle Extract (Silybum Marianum) Manufacturer in India is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.
Export Markets
Quality & Compliance