MEDIOCON INC is a trusted API manufacturer and supplier in India of Mitoguazone API, offering premium-quality pharmaceutical-grade active pharmaceutical ingredients for pharmaceutical manufacturing, oncology formulation development, analytical testing, quality control, stability studies, and research applications. Every batch is manufactured under stringent quality management systems to ensure exceptional purity, consistency, and compliance with international pharmaceutical standards.
Mitoguazone, also known as Methylglyoxal Bis(Guanylhydrazone) (MGBG), is a potent polyamine biosynthesis inhibitor and antineoplastic active pharmaceutical ingredient widely utilized in oncology and cell biology research. It exerts its pharmacological activity by inhibiting S-adenosylmethionine decarboxylase (SAMDC), a key enzyme involved in polyamine synthesis, thereby suppressing cellular proliferation and inducing apoptosis in rapidly dividing cells. Mitoguazone has been extensively investigated for the treatment of leukemia, lymphoma, and various solid tumors and continues to serve as an important compound in cancer pharmacology, medicinal chemistry, formulation development, analytical method validation, process optimization, stability studies, and quality assurance programs.
MEDIOCON INC supplies premium-quality Mitoguazone API across India and to global pharmaceutical manufacturers, biotechnology companies, contract research organizations (CROs), contract development and manufacturing organizations (CDMOs), universities, oncology research institutes, and analytical laboratories. Comprehensive documentation including Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), Technical Data Sheet (TDS), and regulatory support documents are available upon request.
| Parameter | Specification |
|---|---|
| Appearance | White to Off-White Crystalline Powder |
| Identification | IR, UV & HPLC Compliant |
| Assay (HPLC) | ≥99.0% |
| Loss on Drying | NMT 0.50% |
| Residue on Ignition | NMT 0.10% |
| Heavy Metals | NMT 10 ppm |
| pH (1% Solution) | 4.5 – 7.0 |
| Individual Impurity | NMT 0.50% |
| Total Impurities | NMT 1.00% |
| Water Content | NMT 0.50% |
| Melting Point | 210°C – 220°C |
| Solubility | Freely soluble in water; slightly soluble in methanol; practically insoluble in ethanol |
Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Mitoguazone API Manufacturer & Supplier in India | MEDIOCON INC (CAS 54-05-7) and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.
Our Mitoguazone API Manufacturer & Supplier in India | MEDIOCON INC is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.
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