MEDIOCON INC is a trusted global manufacturer and supplier of Naftifine API, offering premium-quality pharmaceutical-grade active pharmaceutical ingredients for pharmaceutical manufacturing, topical formulation development, analytical testing, quality control, stability studies, and research applications. Every batch is manufactured under stringent quality management systems to ensure exceptional purity, consistency, and compliance with international pharmaceutical standards.
Naftifine is a synthetic allylamine antifungal active pharmaceutical ingredient widely used in topical pharmaceutical formulations for the treatment of dermatophyte infections, including tinea pedis (athlete's foot), tinea corporis (ringworm), tinea cruris (jock itch), and other superficial fungal infections. It acts by selectively inhibiting the enzyme squalene epoxidase, disrupting ergosterol biosynthesis and compromising fungal cell membrane integrity, ultimately leading to fungal cell death. In addition to its potent antifungal activity, Naftifine exhibits anti-inflammatory properties, making it highly effective in dermatological formulations. It is extensively utilized in pharmaceutical research, formulation development, analytical method validation, process optimization, stability studies, and quality assurance programs.
MEDIOCON INC supplies premium-quality Naftifine API to pharmaceutical manufacturers, dermatology formulation companies, contract research organizations (CROs), contract development and manufacturing organizations (CDMOs), universities, research institutes, and analytical laboratories worldwide. Comprehensive documentation including Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), Technical Data Sheet (TDS), and regulatory support documents is available upon request.
| Parameter | Specification |
|---|---|
| Appearance | White to Off-White Crystalline Powder |
| Identification | IR, UV & HPLC Compliant |
| Assay (HPLC) | 98.0% – 102.0% |
| Loss on Drying | NMT 0.50% |
| Residue on Ignition | NMT 0.10% |
| Heavy Metals | NMT 10 ppm |
| pH (1% Solution) | 4.5 – 6.5 |
| Individual Impurity | NMT 0.50% |
| Total Impurities | NMT 1.00% |
| Water Content | NMT 0.50% |
| Melting Point | 118°C – 123°C |
| Solubility | Slightly soluble in water; freely soluble in methanol, ethanol, and chloroform |
Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Naftifine API Manufacturer & Supplier (CAS 65473-13-4) and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.
Our Naftifine API Manufacturer & Supplier is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.
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