Active Pharmaceutical Ingredient

Nicergoline API Manufacturer & Supplier

CAS: 27848-84-6 Active Pharmaceutical Ingredient IP / BP / EP / USP GMP Certified Aurangabad, Maharashtra, India
Nicergoline API Manufacturer & Supplier — Mediocon Inc
Nicergoline API Manufacturer & Supplier

Product Overview

CAS No: 27848-84-6 | Grade: IP / BP / EP / USP | Category: Active Pharmaceutical Ingredient

Nicergoline API Manufacturer & Supplier

MEDIOCON INC is a trusted global manufacturer and supplier of Nicergoline API, offering premium-quality pharmaceutical-grade active pharmaceutical ingredients for pharmaceutical manufacturing, formulation development, analytical testing, quality control, stability studies, and research applications. Every batch is manufactured under stringent quality management systems to ensure exceptional purity, consistency, and compliance with international pharmaceutical standards.

Nicergoline is a semisynthetic ergoline derivative widely used in pharmaceutical formulations for the management of cognitive impairment, cerebrovascular insufficiency, vascular dementia, and peripheral vascular disorders. It acts primarily as an alpha-1 adrenergic receptor antagonist, improving cerebral and peripheral blood circulation while enhancing oxygen and glucose utilization in brain tissues. Nicergoline has also been extensively investigated for age-related cognitive decline and neurovascular disorders. Owing to its proven pharmacological profile, Nicergoline is widely utilized in pharmaceutical research, formulation development, analytical method validation, process optimization, stability studies, and quality assurance programs.

MEDIOCON INC supplies premium-quality Nicergoline API to pharmaceutical manufacturers, formulation companies, contract research organizations (CROs), contract development and manufacturing organizations (CDMOs), universities, research institutes, and analytical laboratories worldwide. Comprehensive documentation including Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), Technical Data Sheet (TDS), and regulatory support documents is available upon request.

Product Specifications

Product NameNicergoline API Manufacturer & Supplier
CAS Number27848-84-6
CategoryActive Pharmaceutical Ingredient
GradeIP / BP / EP / USP
AppearanceWhite to Off-White Crystalline Powder
StandardsIP / BP / EP / USP Compliant

Analytical Specifications

ParameterSpecification
AppearanceWhite to Off-White Crystalline Powder
IdentificationIR, UV & HPLC Compliant
Assay (HPLC)98.0% – 102.0%
Loss on DryingNMT 0.50%
Residue on IgnitionNMT 0.20%
Heavy MetalsNMT 10 ppm
pH (1% Solution)5.0 – 7.5
Individual ImpurityNMT 0.50%
Total ImpuritiesNMT 1.50%
Water ContentNMT 0.50%
Melting Point135°C – 140°C
SolubilitySlightly soluble in water; freely soluble in methanol and ethanol

Sourcing, Regulatory & Export Information

Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Nicergoline API Manufacturer & Supplier (CAS 27848-84-6) and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.

Our Nicergoline API Manufacturer & Supplier is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.

Export Markets

  • USA — FDA-registered facility; DMF support available for ANDA/NDA filings
  • Europe — EMA-compliant documentation; CEP/EDMF support on request
  • Africa & Middle East — WHO-GMP certified; competitive pricing for emerging markets
  • Southeast Asia — established logistics network; temperature-controlled shipments
  • India domestic — schedule H/X compliance; all state licensing documentation provided

Quality & Compliance

  • ISO 9001:2015 certified quality management system
  • GMP-certified manufacturing facility, Aurangabad, Maharashtra
  • Full batch traceability from raw material to finished API
  • Dedicated QA team for customer audits and regulatory queries

Frequently Asked Questions — Nicergoline API Manufacturer & Supplier

What is Nicergoline API?
Nicergoline API is a semisynthetic ergoline derivative used in pharmaceutical formulations for improving cerebral and peripheral blood circulation and managing cognitive disorders.
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