Also known as: Vectibix (brand); ABX-EGF; Anti-epidermal growth factor receptor antibody
Panitumumab is a fully human IgG2 monoclonal antibody that binds specifically to the epidermal growth factor receptor (EGFR) and inhibits downstream signaling. It is approved for the treatment of EGFR-expressing metastatic colorectal cancer. Mediocon Inc manufactures this biologic API at its GMP-certified facility in Aurangabad, Maharashtra, India.
| Parameter | Specification |
|---|---|
| CAS Number | 142601-70-1 |
| Molecular Formula | C6462H9948N1716O1993S42 |
| Molecular Weight | ~149,000 g/mol |
| Grade | IP / BP / USP |
| Category | Anti-EGFR Monoclonal Antibody / Antineoplastic |
| Appearance | White to off-white lyophilized powder |
| Solubility | Freely soluble in water, slightly soluble in phosphate buffer |
| Assay | NLT 98.0% |
| Loss on Drying | NMT 0.5% |
| Heavy Metals | NMT 20 ppm |
| Residue on Ignition | NMT 0.1% |
| Microbial Limits | Complies with pharmacopoeia |
| Identification | IR, HPLC Compliant |
| Batch No | PANT24032026 |
| Mfg Date | MAR 2026 |
| Exp Date | FEB 2031 |
| Packing | 25 kg HDPE drums / as per requirement |