Paullinia cupana, commonly known as Guarana, is an Amazonian botanical belonging to the family Sapindaceae. The seeds are the principal plant part used commercially and are naturally rich in caffeine and other xanthine alkaloids, along with polyphenolic compounds. Kew identifies Paullinia cupana Kunth as the accepted botanical name for guarana.
MEDIOCON INC supplies Paullinia cupana (Guarana) extract as a botanical raw material for qualified nutraceutical, food-supplement and functional-food applications. Guarana may be supplied as dried seed powder or as a standardized dry extract, depending on the required specification. The exact caffeine concentration must always be matched to the selected commercial grade.
Guarana's principal characteristic constituent is caffeine, while the seed also contains compounds such as theobromine, theophylline, tannins, catechins and other polyphenolic constituents. Commercial extracts therefore differ significantly depending on extraction solvent, drug-to-extract ratio and standardization.
For a standardized Guarana Seed Dry Extract, the USP describes material prepared from dried Paullinia cupana seeds by water extraction, with a plant-to-native-extract ratio of 5–7:1 and caffeine controlled according to the USP monograph. Because commercial guarana extracts are available at different caffeine strengths, MEDIOCON INC should publish the actual caffeine specification only when it is supported by the supplied batch specification or COA.
For India, there is an important regulatory consideration: FSSAI has issued a direction stating that Paullinia cupana (Guarana) may be used as a source of caffeine when the isolated and purified caffeine meets applicable requirements; however, Guarana extract standardized in caffeine together with other active components, when used as a supplement or nutraceutical ingredient, requires prior approval under the applicable NSF&FI framework.
Caffeine is the principal characteristic stimulant compound associated with Guarana. It occurs naturally in the seeds and is the main marker used for many standardized Guarana extracts.
Guarana naturally contains other methylxanthine compounds, including theobromine and theophylline, although their levels vary according to botanical material and extraction process.
Guarana seeds also contain polyphenolic compounds, including catechins and related constituents that can be used for analytical characterization.
Paullinia cupana extract can be used as a raw material for:
Because Guarana is a caffeine-containing botanical, the finished product must comply with applicable caffeine and food-supplement regulations.
| Parameter | Specification |
|---|---|
| Appearance | Brown to brownish-beige powder |
Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Paullinia cupana (Guarana) Manufacturer & Supplier in India | MEDIOCON INC (CAS 84929-28-2*) and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.
Our Paullinia cupana (Guarana) Manufacturer & Supplier in India | MEDIOCON INC is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.
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