Active Pharmaceutical Ingredient

Phenformin Hydrochloride — CAS 114-86-3

Also known as: Phenethylbiguanide HCl; DBI; Meltrol; DB-01024

GMP Certified IP / BP / EP / USP Biguanide Antidiabetic / Research Chemical Aurangabad, India
Phenformin Hydrochloride API Supplier Manufacturer Aurangabad Maharashtra India — Mediocon Inc
Phenformin Hydrochloride IP / BP / EP / USP  |  GMP Certified  |  Mediocon Inc, Maharashtra, India
CAS No: 114-86-3

Product Overview

Phenformin Hydrochloride is the hydrochloride salt of Phenformin, a biguanide class antidiabetic compound. Mediocon Inc manufactures this high-purity API at its GMP-certified facility in Aurangabad, Maharashtra, India. Although withdrawn from clinical use in many countries due to lactic acidosis risk, Phenformin HCl remains an important research chemical with significant interest in oncology research, where it demonstrates antiproliferative and antitumor effects through AMPK pathway activation.

Therapeutic Applications
  • Oncology research — antiproliferative and antitumor activity via AMPK activation
  • Diabetes research and biguanide mechanism studies
  • Metabolic syndrome research applications
  • Reference standard and pharmaceutical research use

Technical Specifications

ParameterSpecification
CAS Number114-86-3
Molecular FormulaC₁₀H₁₆N₄ · HCl
Molecular Weight241.72 g/mol
GradeIP / BP / EP / USP
CategoryBiguanide Antidiabetic / Research Chemical
AssayNLT 98.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 20 ppm
Residue on IgnitionNMT 0.1%
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Batch NoPHH/24032026
Mfg DateMAR 2026
Exp DateFEB 2031
Packing25 kg HDPE drums / as per requirement

Quality & Compliance

  • GMP Certified manufacturing facility in Aurangabad, Maharashtra, India
  • Full pharmacopoeial compliance: IP / BP / EP / USP standards
  • Complete documentation: Certificate of Analysis (CoA), MSDS, Certificate of Origin
  • Stringent in-process quality control at every manufacturing stage
  • HPLC purity testing and spectroscopic identification (IR, NMR)
  • Cold-chain and controlled-environment storage facilities available
  • Exported to 40+ countries with full regulatory support
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