MEDIOCON INC offers Sceletium tortuosum Extract, a specialty botanical ingredient derived from Sceletium tortuosum, a succulent plant native to South Africa.
Sceletium tortuosum is commonly known as kanna, and it has a long history of traditional use in Southern Africa. Modern research has focused particularly on its characteristic mesembrine-type alkaloids, which are considered important chemical markers of the plant.
The major alkaloid classes reported in Sceletium tortuosum include mesembrine, mesembrenone, mesembrenol and related constituents. Research reviews have identified numerous alkaloids from the plant, with the mesembrine class being predominant.
Sceletium tortuosum Extract is a concentrated botanical ingredient prepared from authenticated Sceletium tortuosum plant material.
The characteristics of the final extract depend on:
Commercial standardized extracts may be characterized by their total alkaloid content or specific mesembrine-type alkaloid profile. One well-characterized commercial extract reported in the scientific literature was standardized to total alkaloids, with mesembrenone and mesembrenol representing the principal fraction and mesembrine controlled as part of the specification.
Scientific Name: Sceletium tortuosum (L.) N.E.Br.
Accepted Taxonomic Name: Mesembryanthemum tortuosum L.
Common Name: Kanna
Traditional Names: Channa, Kougoed
Family: Aizoaceae
Plant Type: Succulent herb
Sceletium tortuosum is endemic to South Africa.
The characteristic phytochemistry of Sceletium includes several alkaloids.
A characteristic mesembrine-type alkaloid and important chemical marker of Sceletium tortuosum.
Another major mesembrine-type alkaloid found in Sceletium extracts.
A naturally occurring Sceletium alkaloid commonly characterized alongside mesembrine and mesembrenone.
Research has identified multiple alkaloids belonging to different structural classes, including mesembrine, Sceletium A4, joubertiamine and tortuosamine classes.
The phytochemical profile of Sceletium can change considerably depending on extraction and processing.
Published research has used hydroethanolic, ethanolic and aqueous extraction approaches, with different extracts demonstrating different chemical profiles.
Therefore, the exact extraction ratio, solvent and alkaloid standardization should be taken from the actual commercial specification rather than assumed.
Sceletium extracts may be standardized using:
A published safety assessment of a standardized Sceletium tortuosum extract reported total alkaloids in the 0.35–0.45% range, with mesembrenone and mesembrenol together representing at least 60% of the alkaloid fraction and mesembrine below 20%. Do not use these numbers as your product specification unless your actual material matches this standardized extract.
Sceletium tortuosum Extract may be used in:
Because Sceletium contains psychoactive alkaloids and regulatory treatment differs between jurisdictions, commercial claims and intended uses should be reviewed against the applicable regulations of the destination market.
Dry botanical extract suitable for incorporation into powders, capsules and tablets.
Extract standardized to a specified total alkaloid or mesembrine-type alkaloid profile.
Concentrated botanical extract converted into a stable dry powder.
MEDIOCON INC can support commercial sourcing requirements with available technical and quality documentation, subject to supplier availability.
Typical documentation may include:
| Parameter | Specification |
|---|---|
| Appearance | Yellowish-brown to brown botanical extract powder |
Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Sceletium tortuosum Extract Manufacturer & Supplier in India | MEDIOCON INC and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.
Our Sceletium tortuosum Extract Manufacturer & Supplier in India | MEDIOCON INC is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.
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