Also known as: Nexavar; BAY 43-9006
Sorafenib is an oral multikinase inhibitor that targets multiple receptor tyrosine kinases (VEGFR, PDGFR) and Raf kinases. It is used in the treatment of hepatocellular carcinoma, renal cell carcinoma, and differentiated thyroid cancer. Mediocon Inc manufactures GMP-compliant Sorafenib API at its Aurangabad facility to international pharmacopoeial standards.
| Parameter | Specification |
|---|---|
| CAS Number | 284461-73-0 |
| Molecular Formula | C₂₁H₁₆ClF₃N₄O₃ |
| Molecular Weight | 464.83 g/mol |
| Grade | IP / BP / EP / USP |
| Category | Anticancer / Kinase Inhibitor |
| Assay | NLT 98.0% |
| Loss on Drying | NMT 0.5% |
| Heavy Metals | NMT 20 ppm |
| Residue on Ignition | NMT 0.1% |
| Microbial Limits | Complies with pharmacopoeia |
| Identification | IR, HPLC Compliant |
| Batch No | SF/25030252 |
| Mfg Date | MAR 2025 |
| Exp Date | FEB 2031 |
| Packing | 25 kg HDPE drums / as per requirement |