Active Pharmaceutical Ingredient

Tacrolimus Monohydrate API Manufacturer & Bulk Supplier in India | MEDIOCON INC

CAS: 109581-93-3 Active Pharmaceutical Ingredient USP / EP / JP / IP GMP Certified Aurangabad, Maharashtra, India
Tacrolimus Monohydrate API Manufacturer & Bulk Supplier in India | MEDIOCON INC — Mediocon Inc
Tacrolimus Monohydrate API Manufacturer & Bulk Supplier in India | MEDIOCON INC

Product Overview

CAS No: 109581-93-3 | Grade: USP / EP / JP / IP | Category: Active Pharmaceutical Ingredient

Tacrolimus Monohydrate API Manufacturer & Bulk Supplier

Tacrolimus Monohydrate API is a premium-quality pharmaceutical-grade Active Pharmaceutical Ingredient (API) widely used in immunosuppressive pharmaceutical formulations for organ transplantation and autoimmune disease management. Tacrolimus Monohydrate is a calcineurin inhibitor that suppresses T-lymphocyte activation, making it one of the most effective immunosuppressive agents used in kidney, liver, heart, and other solid organ transplant therapies. It is also extensively utilized in dermatological formulations for the treatment of atopic dermatitis and other inflammatory skin disorders.

MEDIOCON INC is a trusted Tacrolimus Monohydrate API manufacturer and bulk supplier in India, supplying high-purity pharmaceutical ingredients to pharmaceutical companies, biotechnology organizations, contract manufacturing organizations (CMOs), formulation developers, research laboratories, and international distributors. Our GMP-compliant manufacturing facilities utilize advanced production technologies and stringent quality management systems to ensure superior purity, batch-to-batch consistency, and compliance with international pharmaceutical standards.

Every batch of Tacrolimus Monohydrate API manufactured by MEDIOCON INC undergoes comprehensive analytical testing using validated quality control methods. Critical quality parameters including identity, assay, impurity profile, moisture content, pH, melting point, specific rotation, residual solvents, particle size distribution, microbial limits, and stability are carefully evaluated before commercial release to ensure compliance with stringent pharmaceutical quality specifications.

Our Tacrolimus Monohydrate API is available in USP, EP, JP, IP, and Pharmaceutical Grade, making it suitable for immunosuppressive drug formulations, transplantation medicine, dermatological formulations, analytical testing, formulation development, quality control laboratories, stability studies, and pharmaceutical process validation. We also provide complete regulatory documentation, including Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), Technical Data Sheet (TDS), and supporting regulatory documents, ensuring smooth procurement and regulatory compliance.

With a strong commitment to quality, innovation, and customer satisfaction, MEDIOCON INC has established itself as a dependable global supplier of pharmaceutical raw materials. Through secure packaging, competitive pricing, efficient logistics, and dedicated technical support, we ensure reliable worldwide delivery of premium-quality Tacrolimus Monohydrate API.

If you are looking for a reliable Tacrolimus Monohydrate API manufacturer, exporter, and bulk supplier, MEDIOCON INC offers pharmaceutical-grade ingredients backed by complete documentation, consistent quality, and timely worldwide supply.

Product Specifications

Product NameTacrolimus Monohydrate API Manufacturer & Bulk Supplier in India | MEDIOCON INC
CAS Number109581-93-3
CategoryActive Pharmaceutical Ingredient
GradeUSP / EP / JP / IP
AppearanceWhite to Off-White Crystalline Powder
StandardsUSP / EP / JP / IP

Analytical Specifications

ParameterSpecification
AppearanceWhite to Off-White Crystalline Powder
IdentificationIR, HPLC & UV Complies
Assay (HPLC)98.0% – 102.0%
Loss on DryingNMT 2.0%
Residue on IgnitionNMT 0.2%
Heavy MetalsNMT 10 ppm
pH (1% Solution)5.0 – 7.0
Individual ImpurityNMT 0.5%
Total ImpuritiesNMT 2.0%
Specific Rotation−110° to −125° (c = 1, Chloroform)
Melting Point126°C – 130°C
SolubilityPractically Insoluble in Water; Freely Soluble in Methanol, Ethanol, Chloroform, and Acetonitrile

Sourcing, Regulatory & Export Information

Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Tacrolimus Monohydrate API Manufacturer & Bulk Supplier in India | MEDIOCON INC (CAS 109581-93-3) and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.

Our Tacrolimus Monohydrate API Manufacturer & Bulk Supplier in India | MEDIOCON INC is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.

Export Markets

  • USA — FDA-registered facility; DMF support available for ANDA/NDA filings
  • Europe — EMA-compliant documentation; CEP/EDMF support on request
  • Africa & Middle East — WHO-GMP certified; competitive pricing for emerging markets
  • Southeast Asia — established logistics network; temperature-controlled shipments
  • India domestic — schedule H/X compliance; all state licensing documentation provided

Quality & Compliance

  • ISO 9001:2015 certified quality management system
  • GMP-certified manufacturing facility, Aurangabad, Maharashtra
  • Full batch traceability from raw material to finished API
  • Dedicated QA team for customer audits and regulatory queries

Frequently Asked Questions — Tacrolimus Monohydrate API Manufacturer & Bulk Supplier in India | MEDIOCON INC

What is Tacrolimus Monohydrate API used for?
Tacrolimus Monohydrate API is primarily used in immunosuppressive formulations for organ transplantation, prevention of transplant rejection, autoimmune disorders, and topical treatment of atopic dermatitis.
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