Active Pharmaceutical Ingredient

Tropisetron

Also known as: Navoban; ICS 205-930

CAS: 89565-68-45-HT3 Antagonist APIIP / BP / EP / USPGMP CertifiedAurangabad, Maharashtra, India
Tropisetron API — Mediocon Inc
Tropisetron — Pharmaceutical Grade API | Mediocon Inc, Aurangabad, Maharashtra, India

Product Overview

CAS No: 89565-68-4  |  MF: C₁₇H₂₀N₂O₂  |  MW: 284.36 g/mol

Tropisetron is a high-purity Active Pharmaceutical Ingredient supplied by Mediocon Inc conforming to IP / BP / EP / USP specifications. Manufactured at our GMP-certified facility in Aurangabad, Maharashtra, India.

Tropisetron is a selective serotonin 5-HT3 receptor antagonist used as an antiemetic for the prevention of chemotherapy-induced nausea and vomiting (CINV) and post-operative nausea and vomiting (PONV). It blocks serotonin-mediated signaling in the gut and central nervous system to prevent the emetic reflex.

Key Features

  • High-purity pharmaceutical grade API
  • IP / BP / EP / USP compliant
  • Full CoA and MSDS documentation
  • GMP certified manufacturing facility

Applications

  • Chemotherapy-induced nausea and vomiting (CINV) prevention
  • Post-operative nausea and vomiting (PONV)
  • Radiation therapy-induced emesis
  • 5-HT3 receptor research

Why Choose Mediocon

  • ISO 9001:2015 & GMP certified manufacturing
  • Consistent batch-to-batch quality with full CoA
  • Export-ready documentation: COO, MSDS, DMF
  • Flexible MOQ for both R&D and commercial scale
  • Dedicated QA support for regulatory filings

Product Specifications

Product NameTropisetron
Also Known AsNavoban; ICS 205-930
CAS Number89565-68-4
Molecular FormulaC₁₇H₂₀N₂O₂
Molecular Weight284.36 g/mol
Category5-HT3 Receptor Antagonist / Antiemetic
AppearanceWhite to off-white crystalline powder
SolubilityFreely soluble in water and methanol; soluble in ethanol
GradeIP / BP / EP / USP

Analytical Specifications

ParameterSpecification
AssayNLT 98.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 20 ppm
Residue on IgnitionNMT 0.1%
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Batch No.TPF/24032027
Mfg DateMAR 2026
Exp DateFEB 2031
Packing25 kg HDPE drums / as per requirement
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