Coleus Forskohlii Extract (Coleus forskohlii) Manufacturer in India | Mediocon Inc.

Coleus Forskohlii Extract is a botanical ingredient obtained from Coleus forskohlii, a plant known for its naturally occurring diterpenoid compound forskolin. The extract is used in botanical research and may be evaluated for nutraceutical and other ingredient applications, depending on its grade, composition, and applicable regulations.

Coleus Forskohlii Extract (Coleus forskohlii)

Product Overview

Coleus Forskohlii Extract is derived from Coleus forskohlii, a plant belonging to the Lamiaceae family. It is also known in botanical literature as Plectranthus barbatus. The plant is recognized for forskolin, a naturally occurring labdane-type diterpenoid primarily associated with its root tissue.

The chemical composition of a commercial extract depends on the botanical material, plant part, extraction method, processing conditions, and standardization requirements. Some extracts are standardized to a specified forskolin concentration, while others are supplied with different composition and quality specifications.

For ingredient selection, it is important to confirm the botanical identity, plant part, extract ratio, and forskolin content from the product-specific technical documentation.

Botanical Identity and Source

• Scientific name: Coleus forskohlii (Willd.) Briq.
• Synonym: Plectranthus barbatus Andrews
• Common name: Coleus
• Botanical family: Lamiaceae
• Plant part commonly used for forskolin extraction: Root, particularly the root's cork tissue
• Key compound of interest: Forskolin

Research identifies the root as an important source of forskolin. However, the plant part used for a particular commercial product must be confirmed through its specification and sourcing documentation. <Cite refs={["turn427287search6","turn427287search7"]}/>

Phytochemical Composition of Coleus Forskohlii Extract

1. Forskolin

Forskolin is a labdane-type diterpenoid and the principal marker compound associated with many Coleus extracts. It is widely studied for its ability to activate the enzyme adenylyl cyclase and influence intracellular cyclic AMP (cAMP) signalling.

The concentration of forskolin varies with plant material, growing conditions, chemotype, and extraction process. Standardization claims should therefore be supported by analytical results for the exact extract.

2. Iso-Forskolin

Iso-forskolin is a related compound investigated in phytochemical research. Studies have demonstrated variation in forskolin and iso-forskolin concentrations among plant samples, highlighting the importance of botanical authentication and analytical testing. <Cite refs={["turn427287search1","turn427287search5"]}/>

3. Other Plant Constituents

Depending on the plant material and extraction process, Coleus extracts may contain additional diterpenoids and other plant-derived constituents. The exact profile should be established through suitable analytical methods rather than assumed from the botanical name alone.

Potential Applications of Coleus Forskohlii Extract

1. Botanical and Phytochemical Research

Coleus Forskohlii Extract is relevant to research involving diterpenoids, forskolin quantification, plant chemistry, extraction methods, and botanical standardization.

2. Nutraceutical Formulation Development

Selected Coleus extracts may be evaluated for nutraceutical development where permitted by applicable regulations. Suitability depends on the ingredient's standardization, safety assessment, intended use, and supporting documentation.

3. Botanical Ingredient Research

Researchers and ingredient developers may investigate differences between extract grades, including marker-compound concentration, extraction efficiency, stability, and batch consistency.

4. Analytical and Quality-Control Studies

Coleus materials can be evaluated using chromatographic techniques such as HPLC or HPTLC to identify and quantify specified marker compounds. Validated methods help assess identity, composition, and consistency.

These potential applications do not establish clinical effectiveness or mean that every extract is suitable for every formulation. Any health-related claim must be supported by appropriate evidence and comply with applicable regulations.

Quality Control and Standardization

Quality control is important when selecting Coleus Forskohlii Extract for research or commercial use. Depending on the grade, the specification may include:

• Botanical identification and plant-part verification
• Appearance and physical characteristics
• Forskolin assay, where specified
• Iso-forskolin analysis, where relevant
• Loss on drying or water content
• Residue on ignition or ash values
• Heavy metals and other applicable contaminants
• Microbiological quality
• Residual solvents, where applicable

HPLC or HPTLC may be used to quantify forskolin and related marker compounds. The analytical method, reference standard, and reporting basis should be documented.

A current Certificate of Analysis (CoA) should be reviewed before publishing a numerical forskolin percentage or any other standardized assay claim.

Storage and Handling

Store Coleus Forskohlii Extract according to the product-specific instructions. Use suitable packaging and protect the material from excessive heat, moisture, and other unsuitable storage conditions identified in its technical documentation.

Follow the relevant safety data sheet and handling procedures.

Selecting the Right Coleus Forskohlii Extract

When selecting an extract, buyers should verify the scientific name, plant part, extraction method, extract ratio, forskolin concentration, analytical method, and intended application.

Two products labelled Coleus Extract may have different compositions and standardization levels. Comparing the technical data sheet and batch-specific CoA helps buyers assess whether the material meets their requirements.

Conclusion

Coleus Forskohlii Extract is a botanical ingredient of interest because of its naturally occurring diterpenoid compound, forskolin. Its composition and suitability depend on the plant material, extraction process, standardization, analytical testing, and intended use.

For informed ingredient selection, review the product specification, botanical identity, and batch-specific Certificate of Analysis before making purchasing or formulation decisions.