Active Pharmaceutical Ingredient

Fludarabine

Also known as: Fludara (brand)

CAS: 21679-14-1 Antineoplastic / Chemotherapy IP / BP / USP Bulk Supply Available
Fludarabine API Manufacturer India | Mediocon Inc
Fludarabine — Pharmaceutical Grade API

Product Overview

CAS No: 21679-14-1  |  MF: C₁₀H₁₂FN₅O₄  |  MW: 285.23 g/mol

Fludarabine is a purine analogue antimetabolite used in the treatment of B-cell chronic lymphocytic leukemia (CLL) and other hematological malignancies. It inhibits DNA synthesis by competing with adenosine and interfering with DNA polymerase and ribonucleotide reductase.

Mediocon Inc supplies Fludarabine IP/BP/USP as a certified active pharmaceutical ingredient for oncology pharmaceutical manufacturers. Manufactured under GMP-certified conditions with comprehensive quality controls and complete regulatory documentation for global compliance.

Key Features

  • Purine analogue antimetabolite
  • Inhibits DNA polymerase
  • GMP certified manufacturing
  • Suitable for oncology formulations

Applications

  • Chronic lymphocytic leukemia (CLL) therapy
  • Non-Hodgkin lymphoma treatments
  • Conditioning regimens for bone marrow transplant
  • Oncology research & clinical trials

Why Choose Mediocon

  • ISO 9001:2015 & GMP certified manufacturing
  • Consistent batch-to-batch quality with full CoA
  • Export-ready documentation: COO, MSDS, DMF
  • Flexible MOQ for both R&D and commercial scale
  • Dedicated QA support for regulatory filings

Product Specifications

Product NameFludarabine
CAS Number21679-14-1
Molecular FormulaC₁₀H₁₂FN₅O₄
Molecular Weight285.23 g/mol
CategoryAntineoplastic / Chemotherapy
AppearanceWhite to Off-White Powder
GradeIP / BP / USP
Packaging25 kg HDPE Drums / Aluminium Bags
StorageCool, Dry & Ventilated Place

Analytical Specifications

ParameterSpecification
AssayNLT 98.0% & NMT 102.0%
Loss on DryingNMT 1.0%
Heavy MetalsNMT 10 ppm
Residual SolventsComplies ICH Q3C
Microbial LimitsComplies
IdentificationHPLC / UV Compliant
pH (1% solution)3.0 – 4.5
Packing25 kg HDPE drums / as per requirement
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