Active Pharmaceutical Ingredient

Flumazenil

Also known as: Romazicon / Anexate (brand)

CAS: 78755-81-4 Benzodiazepine Antagonist IP / BP / USP Bulk Supply Available
Flumazenil API Manufacturer India | Mediocon Inc
Flumazenil — Pharmaceutical Grade API

Product Overview

CAS No: 78755-81-4  |  MF: C₁₅H₁₄FN₃O₃  |  MW: 303.29 g/mol

Flumazenil is a competitive benzodiazepine receptor antagonist used for the reversal of benzodiazepine-induced sedation and to manage benzodiazepine overdose. It acts at GABA-A receptors, rapidly reversing CNS depression caused by benzodiazepine agents.

Mediocon Inc manufactures Flumazenil IP/BP/USP with high purity suitable for parenteral and injectable pharmaceutical formulations across critical care settings. Every batch undergoes rigorous quality testing ensuring full compliance with pharmacopoeial standards.

Key Features

  • Competitive benzodiazepine receptor antagonist
  • Rapid onset reversal agent
  • Injectable/parenteral grade purity
  • Meets IP/BP/USP pharmacopoeial standards

Applications

  • ICU sedation reversal formulations
  • Anesthesia reversal injectable products
  • Benzodiazepine overdose management
  • Emergency medicine pharmaceutical manufacturing

Why Choose Mediocon

  • ISO 9001:2015 & GMP certified manufacturing
  • Consistent batch-to-batch quality with full CoA
  • Export-ready documentation: COO, MSDS, DMF
  • Flexible MOQ for both R&D and commercial scale
  • Dedicated QA support for regulatory filings

Product Specifications

Product NameFlumazenil
CAS Number78755-81-4
Molecular FormulaC₁₅H₁₄FN₃O₃
Molecular Weight303.29 g/mol
CategoryBenzodiazepine Antagonist
AppearanceWhite to Off-White Crystalline Powder
GradeIP / BP / USP
Packaging25 kg HDPE Drums / Aluminium Bags
StorageCool, Dry & Ventilated Place

Analytical Specifications

ParameterSpecification
AssayNLT 98.0% & NMT 102.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 10 ppm
Residual SolventsComplies ICH Q3C
Microbial LimitsComplies
IdentificationHPLC & IR Compliant
pH (1% solution)4.5 – 6.5
Packing25 kg HDPE drums / as per requirement
💬
Mediocon AI
Hello 👋 How can I help you today?