Active Pharmaceutical Ingredient

Flunarizine

Also known as: Sibelium (brand)

CAS: 52468-60-7 Calcium Channel Blocker / Antimigraine IP / BP / USP Bulk Supply Available
Flunarizine API Manufacturer India | Mediocon Inc
Flunarizine — Pharmaceutical Grade API

Product Overview

CAS No: 52468-60-7  |  MF: C₂₆H₂₆F₂N₂  |  MW: 404.50 g/mol

Flunarizine is a selective calcium entry blocker used for the prophylactic treatment of migraine, vertigo, and peripheral vascular disease. It blocks voltage-dependent calcium channels and exhibits antihistaminic and dopamine D2 receptor blocking properties.

Mediocon Inc supplies Flunarizine IP/BP/USP as a pharmaceutical-grade API for manufacturers producing antimigraine and neurological formulations. With robust quality controls and GMP-certified manufacturing, we ensure consistent purity and efficacy in every batch.

Key Features

  • Selective calcium channel blocker
  • Antimigraine & antivertigo action
  • Dopamine D2 antagonist activity
  • Stable shelf life with proper storage

Applications

  • Migraine prophylaxis tablets & capsules
  • Vertigo treatment formulations
  • Peripheral vascular disease therapy
  • Neurological & CNS product manufacturing

Why Choose Mediocon

  • ISO 9001:2015 & GMP certified manufacturing
  • Consistent batch-to-batch quality with full CoA
  • Export-ready documentation: COO, MSDS, DMF
  • Flexible MOQ for both R&D and commercial scale
  • Dedicated QA support for regulatory filings

Product Specifications

Product NameFlunarizine
CAS Number52468-60-7
Molecular FormulaC₂₆H₂₆F₂N₂
Molecular Weight404.50 g/mol
CategoryCalcium Channel Blocker / Antimigraine
AppearanceWhite to Off-White Powder
GradeIP / BP / USP
Packaging25 kg HDPE Drums / Aluminium Bags
StorageCool, Dry & Ventilated Place

Analytical Specifications

ParameterSpecification
AssayNLT 98.0% & NMT 102.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 10 ppm
Residual SolventsComplies ICH Q3C
Microbial LimitsComplies
IdentificationHPLC & IR Compliant
Melting Point252 – 256 °C
Packing25 kg HDPE drums / as per requirement
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