MEDIOCON INC – Lacidipine is a dihydropyridine calcium-channel blocker used as an antihypertensive pharmaceutical active ingredient. It selectively inhibits the influx of calcium ions through L-type calcium channels in vascular smooth muscle, producing vasodilation and reduction of peripheral vascular resistance. Lacidipine has the molecular formula C₂₆H₃₃NO₆ and molecular weight approximately 455.55 g/mol.
Lacidipine is a synthetic dihydropyridine derivative belonging to the calcium-channel blocker class. Its primary pharmacological effect is relaxation of vascular smooth muscle, which results in decreased peripheral vascular resistance and reduction of blood pressure.
Lacidipine is identified by CAS 103890-78-4.
Product Name: Lacidipine
CAS Number: 103890-78-4
Molecular Formula: C₂₆H₃₃NO₆
Molecular Weight: 455.55 g/mol
Chemical Class: Dihydropyridine calcium-channel blocker
Therapeutic Class: Antihypertensive / Calcium-channel blocker
IUPAC Name: 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-[2-[3-(1,1-dimethylethoxy)-3-oxopropyl]oxy]-1,1-dimethylethyl ester 5-ethyl ester
Synonyms: Lacidipine, Lacipil
PubChem CID: 5311067
Lacidipine blocks L-type calcium channels, particularly in vascular smooth muscle. This reduces calcium entry into smooth-muscle cells and produces arterial vasodilation.
The resulting reduction in peripheral vascular resistance contributes to lowering of systemic blood pressure.
MEDIOCON INC focuses on supplying pharmaceutical and specialty chemical ingredients with emphasis on quality, consistency, technical documentation and reliable supply.
Lacidipine quality evaluation may include identification, assay, chromatographic purity, related substances, residual solvents, water content, residue on ignition and other parameters according to the applicable product specification.
The exact analytical acceptance criteria should be confirmed against the current approved specification and batch-specific Certificate of Analysis.
Lacidipine is primarily used as an antihypertensive pharmaceutical ingredient. It may be used alone or in combination with other antihypertensive medicines according to the applicable approved formulation and prescribing information.
Lacidipine is generally described as a yellow crystalline powder. It is practically insoluble in water and soluble in certain organic solvents.
Appearance: Yellow crystalline powder
Product availability, packaging configuration, Certificate of Analysis (COA), Safety Data Sheet (SDS/MSDS), technical specifications and other documentation should be confirmed with MEDIOCON INC according to the intended application and customer requirements.
| Parameter | Specification |
|---|---|
| Appearance | Yellow crystalline powder |
Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Lacidipine API Manufacturer and Supplier in India (CAS 103890-78-4) and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.
Our Lacidipine API Manufacturer and Supplier in India is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.
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