MEDIOCON INC – Lafutidine is a second-generation histamine H₂-receptor antagonist with gastroprotective activity. It reduces gastric acid secretion through H₂-receptor blockade and has been used in the management of acid-related gastrointestinal disorders. Lafutidine has the molecular formula C₂₂H₂₉N₃O₄S and molecular weight approximately 431.55 g/mol.
Lafutidine is a synthetic H₂-receptor antagonist belonging to the antiulcer pharmaceutical class. In addition to inhibiting histamine-stimulated gastric acid secretion, Lafutidine has been described as having gastroprotective activity.
Lafutidine is associated with the chemical identifier CAS 118288-08-7 for the free-base/active stereochemical form. CAS 206449-93-6 is also listed in chemical databases for Lafutidine, so the exact stereochemical/product identity should be matched with the applicable specification.
Product Name: Lafutidine
CAS Number: 118288-08-7
Alternate CAS: 206449-93-6
Molecular Formula: C₂₂H₂₉N₃O₄S
Molecular Weight: 431.55 g/mol
Chemical Class: Histamine H₂-receptor antagonist
Therapeutic Class: Antiulcer / Gastrointestinal agent
Synonyms: FRG-8813, Lafutidine, (+)-Lafutidine
PubChem CID: 5282136
UNII: 49S4O7ADLC
ChEBI ID: CHEBI:31759
ChEMBL ID: CHEMBL1742461
DrugBank ID: DB12770
Lafutidine acts primarily as a histamine H₂-receptor antagonist. By blocking H₂ receptors on gastric parietal cells, it reduces histamine-mediated gastric acid secretion.
Lafutidine has also been reported to have gastroprotective effects in addition to its antisecretory activity.
MEDIOCON INC focuses on supplying pharmaceutical and specialty chemical ingredients with emphasis on quality, consistency, technical documentation and reliable supply.
Lafutidine quality evaluation may include identification, assay, chromatographic purity, related substances, residual solvents, water content, residue on ignition and other parameters according to the applicable product specification.
The exact analytical acceptance criteria should be confirmed against the current approved specification and batch-specific Certificate of Analysis.
Lafutidine is an H₂-receptor antagonist used for acid-related gastrointestinal conditions, including peptic-ulcer-related disorders and gastroesophageal reflux disease in markets where it is approved.
Lafutidine is reported as a white to off-white solid/powder. TCI lists it as a solid at 20°C, while MedChemExpress describes the material as white to off-white.
Appearance: White to off-white powder / solid
Product availability, packaging configuration, Certificate of Analysis (COA), Safety Data Sheet (SDS/MSDS), technical specifications and other documentation should be confirmed with MEDIOCON INC according to the intended application and customer requirements.
| Parameter | Specification |
|---|---|
| Appearance | White to off-white powder |
Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Lafutidine API Manufacturer and Supplier in India (CAS 118288-08-7) and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.
Our Lafutidine API Manufacturer and Supplier in India is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.
Export Markets
Quality & Compliance