MEDIOCON INC – Lecozotan is a synthetic small-molecule compound that has been investigated primarily for its activity as a selective 5-HT₁A receptor antagonist. It has been studied for potential cognitive-enhancing effects and in research related to Alzheimer's disease.
Lecozotan is also known as SRA-333 and is a selective serotonin 5-HT₁A receptor antagonist. Research has investigated its effects on neurotransmitter release, including glutamate and acetylcholine, and its potential application in cognitive and neurological research.
Lecozotan has been investigated in clinical research related to Alzheimer's disease, but it should not be represented as an approved treatment unless the applicable regulatory approval has been specifically established for the intended market.
Product Name: Lecozotan
CAS Number: 434283-16-6
Molecular Formula: C₂₈H₂₉N₅O₃
Molecular Weight: Approximately 483.6 g/mol
Chemical Class: Synthetic small-molecule 5-HT₁A receptor antagonist
Synonyms: SRA-333, Lecozotan, Lecozotanum
PubChem CID: 10116877
ChEMBL ID: CHEMBL372205
UNII: 48854OTZ5E
Lecozotan acts as a selective antagonist of the serotonin 5-HT₁A receptor. Research on the hydrochloride form reports a Ki of approximately 4.5 nM for the cloned human 5-HT₁A receptor. Studies have also reported enhancement of stimulated glutamate and acetylcholine release in the hippocampus.
MEDIOCON INC focuses on supplying pharmaceutical and specialty chemical ingredients with emphasis on quality, consistency, technical documentation and dependable supply.
Lecozotan quality evaluation may include identity, assay, chromatographic purity, related substances, residual solvents, water content, residue on ignition and other parameters according to the applicable product specification.
The exact analytical acceptance criteria should be confirmed against the current approved specification and batch-specific Certificate of Analysis.
Lecozotan has been investigated primarily as a 5-HT₁A receptor antagonist and as a potential cognitive-enhancing compound. Research has included studies related to Alzheimer's disease and neurological function.
Lecozotan is a defined synthetic small molecule with molecular formula C₂₈H₂₉N₅O₃ and molecular weight approximately 483.6 g/mol. The free compound is identified by CAS 434283-16-6.
Lecozotan hydrochloride is a separate salt form with CAS 433282-68-9, molecular formula C₂₈H₃₀ClN₅O₃ and molecular weight 520.02 g/mol.
Product availability, packaging configuration, Certificate of Analysis (COA), Safety Data Sheet (SDS/MSDS), technical specifications and other documentation should be confirmed with MEDIOCON INC according to the intended application and customer requirements.
Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Lecozotan API Manufacturer and Supplier in India (CAS 434283-16-6) and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.
Our Lecozotan API Manufacturer and Supplier in India is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.
Export Markets
Quality & Compliance