MEDIOCON INC is a trusted global manufacturer and supplier of Midodrine Hydrochloride API in India, offering high-quality pharmaceutical-grade active pharmaceutical ingredients for pharmaceutical manufacturing, formulation development, analytical testing, quality control, stability studies, and research applications. Our APIs are supplied with appropriate quality documentation to support pharmaceutical development, manufacturing, and quality-assurance requirements.
Midodrine Hydrochloride is a vasopressor and antihypotensive active pharmaceutical ingredient belonging to the sympathomimetic class. Midodrine is a prodrug that is converted to its active metabolite, desglymidodrine, which selectively activates peripheral alpha-1 adrenergic receptors in arteriolar and venous vasculature. This produces vasoconstriction and increases blood pressure. Midodrine Hydrochloride is primarily used in pharmaceutical formulations for the treatment of symptomatic orthostatic hypotension.
Midodrine Hydrochloride is the hydrochloride salt of Midodrine and is chemically identified as 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide hydrochloride. It has the molecular formula C₁₂H₁₈N₂O₄·HCl, molecular weight 290.74 g/mol, and CAS Number 43218-56-0. It is described as a white crystalline powder, soluble in water and sparingly soluble in methanol, with a melting range of approximately 200°C–203°C.
MEDIOCON INC supplies premium-quality Midodrine Hydrochloride API to pharmaceutical manufacturers, contract manufacturing organizations (CMOs), contract research organizations (CROs), formulation companies, biotechnology companies, universities, research institutes, and analytical laboratories worldwide, supported with comprehensive documentation including COA, MSDS, technical data sheets, product specifications, analytical documentation, and applicable quality documents.
| Parameter | Specification |
|---|---|
| Appearance | White Crystalline Powder |
| Identification | IR / HPLC / Chloride Complies |
| Assay (HPLC) | 98.0% – 102.0% |
| Loss on Drying | NMT 1.0% |
| Residue on Ignition | NMT 0.5% |
| Heavy Metals | NMT 20 ppm |
| pH (1% Solution) | 3.5 – 5.5 |
| Individual Impurity | NMT 0.5% |
| Total Impurities | NMT 1.0% |
| Water Content | NMT 1.0% |
| Melting Point | 200°C – 203°C |
| Solubility | Soluble in water; sparingly soluble in methanol |
Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Midodrine Hydrochloride API Manufacturer & Supplier in India | MEDIOCON INC (CAS 43218-56-0) and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.
Our Midodrine Hydrochloride API Manufacturer & Supplier in India | MEDIOCON INC is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.
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