MEDIOCON INC is a trusted API manufacturer and supplier in India of Motesanib API, delivering premium-quality pharmaceutical-grade active pharmaceutical ingredients for pharmaceutical manufacturing, oncology formulation development, analytical testing, quality control, stability studies, and pharmaceutical research. Every batch is manufactured under stringent quality management systems to ensure exceptional purity, consistency, and compliance with international pharmaceutical standards.
Motesanib is a potent multi-targeted tyrosine kinase inhibitor (TKI) widely used in pharmaceutical research and oncology drug development. It selectively inhibits vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3), platelet-derived growth factor receptor (PDGFR), and KIT receptor tyrosine kinase, thereby suppressing tumor angiogenesis and inhibiting cancer cell growth. Motesanib has been extensively investigated for the treatment of non-small cell lung cancer (NSCLC), thyroid cancer, colorectal cancer, and other solid tumors. Owing to its anti-angiogenic activity, it is widely utilized in oncology pharmaceutical research, formulation development, analytical method validation, process optimization, stability studies, and quality assurance programs.
MEDIOCON INC supplies premium-quality Motesanib API across India and to global pharmaceutical manufacturers, biotechnology companies, contract research organizations (CROs), contract development and manufacturing organizations (CDMOs), universities, research institutes, and analytical laboratories. Comprehensive documentation including Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), Technical Data Sheet (TDS), and regulatory support documents is available upon request.
| Parameter | Specification |
|---|---|
| Appearance | White to Off-White Crystalline Powder |
| Identification | IR, UV & HPLC Compliant |
| Assay (HPLC) | ≥99.0% |
| Loss on Drying | NMT 0.50% |
| Residue on Ignition | NMT 0.10% |
| Heavy Metals | NMT 10 ppm |
| pH (1% Solution) | 5.0 – 7.5 |
| Individual Impurity | NMT 0.50% |
| Total Impurities | NMT 1.00% |
| Water Content | NMT 0.50% |
| Melting Point | 210°C – 215°C |
| Solubility | Slightly soluble in water; freely soluble in DMSO and methanol |
Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Motesanib API Manufacturer & Supplier in India | MEDIOCON INC (CAS 453562-69-1) and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.
Our Motesanib API Manufacturer & Supplier in India | MEDIOCON INC is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.
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