Active Pharmaceutical Ingredient

Pentostatin — CAS 53910-25-1

Also known as: 2'-Deoxycoformycin; DCF; Nipent (brand); Co-Vidarabine

GMP Certified IP / BP / EP / USP Antineoplastic / ADA Inhibitor Aurangabad, India
Pentostatin API Supplier Manufacturer Aurangabad Maharashtra India — Mediocon Inc
Pentostatin IP / BP / EP / USP  |  GMP Certified  |  Mediocon Inc, Maharashtra, India
CAS No: 53910-25-1

Product Overview

Pentostatin (2'-Deoxycoformycin) is a potent antineoplastic agent that acts as a purine analogue and inhibitor of adenosine deaminase (ADA). Mediocon Inc manufactures this high-purity oncology API at its GMP-certified facility in Aurangabad, Maharashtra, India. Pentostatin is used in the treatment of hairy cell leukemia and has demonstrated efficacy in other lymphoid malignancies. Its mechanism involves ADA inhibition leading to accumulation of toxic deoxyadenosine in lymphocytes.

Therapeutic Applications
  • Hairy cell leukemia (HCL) treatment — first-line therapy
  • Chronic lymphocytic leukemia (CLL) in refractory cases
  • Cutaneous T-cell lymphoma management
  • Graft-versus-host disease (GvHD) prophylaxis research

Technical Specifications

ParameterSpecification
CAS Number53910-25-1
Molecular FormulaC₁₁H₁₆N₄O₄
Molecular Weight268.27 g/mol
GradeIP / BP / EP / USP
CategoryAntineoplastic / ADA Inhibitor
AssayNLT 98.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 20 ppm
Residue on IgnitionNMT 0.1%
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Batch NoPTS/24032026
Mfg DateMAR 2026
Exp DateFEB 2031
Packing25 kg HDPE drums / as per requirement

Quality & Compliance

  • GMP Certified manufacturing facility in Aurangabad, Maharashtra, India
  • Full pharmacopoeial compliance: IP / BP / EP / USP standards
  • Complete documentation: Certificate of Analysis (CoA), MSDS, Certificate of Origin
  • Stringent in-process quality control at every manufacturing stage
  • HPLC purity testing and spectroscopic identification (IR, NMR)
  • Cold-chain and controlled-environment storage facilities available
  • Exported to 40+ countries with full regulatory support
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