Also known as: 2'-Deoxycoformycin; DCF; Nipent (brand); Co-Vidarabine
Pentostatin (2'-Deoxycoformycin) is a potent antineoplastic agent that acts as a purine analogue and inhibitor of adenosine deaminase (ADA). Mediocon Inc manufactures this high-purity oncology API at its GMP-certified facility in Aurangabad, Maharashtra, India. Pentostatin is used in the treatment of hairy cell leukemia and has demonstrated efficacy in other lymphoid malignancies. Its mechanism involves ADA inhibition leading to accumulation of toxic deoxyadenosine in lymphocytes.
| Parameter | Specification |
|---|---|
| CAS Number | 53910-25-1 |
| Molecular Formula | C₁₁H₁₆N₄O₄ |
| Molecular Weight | 268.27 g/mol |
| Grade | IP / BP / EP / USP |
| Category | Antineoplastic / ADA Inhibitor |
| Assay | NLT 98.0% |
| Loss on Drying | NMT 0.5% |
| Heavy Metals | NMT 20 ppm |
| Residue on Ignition | NMT 0.1% |
| Microbial Limits | Complies with pharmacopoeia |
| Identification | IR, HPLC Compliant |
| Batch No | PTS/24032026 |
| Mfg Date | MAR 2026 |
| Exp Date | FEB 2031 |
| Packing | 25 kg HDPE drums / as per requirement |