Also known as: 4-Hydroperoxycyclophosphamide; 4-HC; Pergamide
Perfosfamide (4-Hydroperoxycyclophosphamide) is an active oxazaphosphorine alkylating agent used in oncology applications. Mediocon Inc manufactures this high-purity API at its GMP-certified facility in Aurangabad, Maharashtra, India. Perfosfamide is a chemically activated form of cyclophosphamide that does not require hepatic bioactivation, making it particularly valuable for ex vivo bone marrow purging and direct antitumor applications. It cross-links DNA strands, preventing cancer cell replication.
| Parameter | Specification |
|---|---|
| CAS Number | 62435-42-1 |
| Molecular Formula | C₇H₁₅Cl₂N₂O₃P |
| Molecular Weight | 293.08 g/mol |
| Grade | IP / BP / EP / USP |
| Category | Antineoplastic / Alkylating Agent |
| Assay | NLT 98.0% |
| Loss on Drying | NMT 0.5% |
| Heavy Metals | NMT 20 ppm |
| Residue on Ignition | NMT 0.1% |
| Microbial Limits | Complies with pharmacopoeia |
| Identification | IR, HPLC Compliant |
| Batch No | PFS/24032026 |
| Mfg Date | MAR 2026 |
| Exp Date | FEB 2031 |
| Packing | 25 kg HDPE drums / as per requirement |