Active Pharmaceutical Ingredient

Tipifarnib

Also known as: Zarnestra; R115777

CAS: 192185-72-1Anticancer APIFarnesyltransferase InhibitorIP / BP / EP / USPGMP CertifiedAurangabad, India
Tipifarnib API — Mediocon Inc
Tipifarnib — Pharmaceutical Grade API | Mediocon Inc, Aurangabad, Maharashtra, India

Product Overview

CAS No: 192185-72-1  |  MF: C₂₂H₁₈Cl₂FN₃O  |  MW: 422.30 g/mol

Tipifarnib is a high-purity Active Pharmaceutical Ingredient supplied by Mediocon Inc conforming to IP / BP / EP / USP specifications. Manufactured at our GMP-certified facility in Aurangabad, Maharashtra, India.

Tipifarnib is a potent and selective farnesyltransferase inhibitor used in the treatment of relapsed or refractory peripheral T-cell lymphoma (PTCL) and hematologic malignancies. It prevents RAS protein farnesylation, inhibiting tumor cell proliferation.

Key Features

  • High-purity pharmaceutical grade API
  • IP / BP / EP / USP compliant
  • Full CoA and MSDS documentation
  • GMP certified manufacturing facility

Applications

  • Peripheral T-cell lymphoma (PTCL) treatment
  • Hematologic malignancies
  • HRAS-mutant head and neck squamous cell carcinoma
  • Oncology research

Why Choose Mediocon

  • ISO 9001:2015 & GMP certified manufacturing
  • Consistent batch-to-batch quality with full CoA
  • Export-ready documentation: COO, MSDS, DMF
  • Flexible MOQ for both R&D and commercial scale
  • Dedicated QA support for regulatory filings

Product Specifications

Product NameTipifarnib
Also Known AsZarnestra; R115777
CAS Number192185-72-1
Molecular FormulaC₂₂H₁₈Cl₂FN₃O
Molecular Weight422.30 g/mol
CategoryFarnesyltransferase Inhibitor / Anticancer API
AppearanceWhite to off-white crystalline powder
SolubilitySlightly soluble in water; freely soluble in DMSO and methanol
GradeIP / BP / EP / USP

Analytical Specifications

ParameterSpecification
AssayNLT 98.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 20 ppm
Residue on IgnitionNMT 0.1%
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Batch No.TPF/24032026
Mfg DateMAR 2026
Exp DateFEB 2031
Packing25 kg HDPE drums / as per requirement
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