Active Pharmaceutical Ingredient

Tirapazamine

Also known as: SR 4233; WIN 59075

CAS: 27314-97-2Anticancer APIHypoxic CytotoxinIP / BP / EP / USPGMP CertifiedAurangabad, India
Tirapazamine API — Mediocon Inc
Tirapazamine — Pharmaceutical Grade API | Mediocon Inc, Aurangabad, Maharashtra, India

Product Overview

CAS No: 27314-97-2  |  MF: C₇H₈N₄O₂  |  MW: 180.16 g/mol

Tirapazamine is a high-purity Active Pharmaceutical Ingredient supplied by Mediocon Inc conforming to IP / BP / EP / USP specifications. Manufactured at our GMP-certified facility in Aurangabad, Maharashtra, India.

Tirapazamine is a bioreductive prodrug that is selectively toxic to hypoxic tumour cells. It is activated under low-oxygen conditions to generate cytotoxic radical species causing DNA strand breaks, making it an important investigational anticancer agent.

Key Features

  • High-purity pharmaceutical grade API
  • IP / BP / EP / USP compliant
  • Full CoA and MSDS documentation
  • GMP certified manufacturing facility

Applications

  • Hypoxic tumour cell cytotoxicity
  • Combination cancer chemotherapy
  • Head and neck cancer research
  • Bioreductive anticancer research

Why Choose Mediocon

  • ISO 9001:2015 & GMP certified manufacturing
  • Consistent batch-to-batch quality with full CoA
  • Export-ready documentation: COO, MSDS, DMF
  • Flexible MOQ for both R&D and commercial scale
  • Dedicated QA support for regulatory filings

Product Specifications

Product NameTirapazamine
Also Known AsSR 4233; WIN 59075
CAS Number27314-97-2
Molecular FormulaC₇H₈N₄O₂
Molecular Weight180.16 g/mol
CategoryHypoxic Cytotoxin / Anticancer API
AppearanceYellow crystalline powder
SolubilitySlightly soluble in water; soluble in DMSO and methanol
GradeIP / BP / EP / USP

Analytical Specifications

ParameterSpecification
AssayNLT 98.0%
Loss on DryingNMT 0.5%
Heavy MetalsNMT 20 ppm
Residue on IgnitionNMT 0.1%
Microbial LimitsComplies with pharmacopoeia
IdentificationIR, HPLC Compliant
Batch No.TRP/24032026
Mfg DateMAR 2026
Exp DateFEB 2031
Packing25 kg HDPE drums / as per requirement
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