MEDIOCON INC – Landiolol is a short-acting, highly selective β1-adrenergic receptor blocker belonging to the ultra-short-acting beta-blocker class. It is used in cardiovascular medicine for rapid control of heart rate and has a particularly short duration of action. Landiolol is identified by CAS 133242-30-5, with molecular formula C₂₅H₃₉N₃O₈ and molecular weight approximately 509.59 g/mol.
Landiolol is a synthetic beta-adrenergic receptor antagonist with high selectivity for β1 receptors. Because of its rapid onset and short duration of action, it is particularly useful when controlled, rapidly reversible reduction of heart rate is required.
Landiolol is commonly supplied clinically as Landiolol Hydrochloride, the hydrochloride salt of the active moiety. The hydrochloride has CAS 144481-98-1 and molecular weight approximately 546.1 g/mol.
Product Name: Landiolol
CAS Number: 133242-30-5
Molecular Formula: C₂₅H₃₉N₃O₈
Molecular Weight: Approximately 509.59 g/mol
Chemical Class: Ultra-short-acting selective β1-adrenergic receptor blocker
Synonyms: ONO-1101, ONO1101, AOP-200704, LDLL-600
PubChem CID: 114905
ChEBI ID: CHEBI:135809
DrugBank ID: DB12212
The CAS number, molecular formula and molecular weight are confirmed by PubChem and FDA substance records.
Landiolol selectively blocks β1-adrenergic receptors in the heart. This decreases the effects of sympathetic stimulation on cardiac activity, resulting in reduced heart rate and decreased cardiac workload.
Its high β1 selectivity and very short duration of action allow rapid adjustment of its cardiovascular effects when administered under appropriate medical supervision.
MEDIOCON INC focuses on supplying pharmaceutical and specialty chemical ingredients with emphasis on quality, consistency, technical documentation and reliable supply.
Landiolol quality evaluation may include identification, assay, chromatographic purity, related substances, residual solvents, water content, residue on ignition and other parameters according to the applicable product specification.
The exact analytical acceptance criteria should be confirmed against the current approved specification and batch-specific Certificate of Analysis.
Landiolol is used as a short-acting β1-selective beta-blocker for rapid control of heart rate in appropriate cardiovascular settings. It has applications where rapid titration and rapid offset of beta-blockade are desirable.
The exact indication, formulation and regulatory status should be confirmed according to the applicable market authorization and current prescribing information.
Landiolol is a defined synthetic small molecule with molecular formula C₂₅H₃₉N₃O₈ and molecular weight approximately 509.59 g/mol.
The hydrochloride salt has the molecular formula C₂₅H₄₀ClN₃O₈ and molecular weight approximately 546.1 g/mol.
Appearance: Not reliably available / Cannot be verified for the free-base API without a product-specific specification.
Product availability, packaging configuration, Certificate of Analysis (COA), Safety Data Sheet (SDS/MSDS), technical specifications and other documentation should be confirmed with MEDIOCON INC according to the intended application and customer requirements.
Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Landiolol API Manufacturer and Supplier in India (CAS 133242-30-5) and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.
Our Landiolol API Manufacturer and Supplier in India is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.
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