MEDIOCON INC is a trusted global manufacturer and supplier of Mevastatin API in India, offering high-quality pharmaceutical and research-grade active pharmaceutical ingredients for pharmaceutical research, formulation development, analytical testing, quality control, medicinal chemistry, stability studies, and biotechnology applications. Our APIs are supplied with appropriate quality documentation to support pharmaceutical development and research requirements.
Mevastatin, also known as Compactin or ML-236B, is a naturally occurring statin and inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, an important enzyme involved in cholesterol biosynthesis. It was originally isolated from species of Penicillium, including Penicillium citrinum and Penicillium brevicompactum. Mevastatin has played an important role in the development and study of HMG-CoA reductase inhibitors and is widely used in biochemical, pharmacological, lipid-metabolism, and drug-discovery research.
Mevastatin has the molecular formula C₂₃H₃₄O₅, molecular weight 390.50 g/mol, and CAS Number 73573-88-3. PubChem identifies Mevastatin as a statin and HMG-CoA reductase inhibitor, while current commercial reference material is reported as a white to light-yellow powder or crystalline solid, with ≥98% HPLC purity and a melting point around 151°C.
Due to its established activity against HMG-CoA reductase, Mevastatin is utilized in cholesterol-biosynthesis research, statin research, enzyme inhibition studies, lipid metabolism research, cardiovascular drug discovery, analytical method development, and pharmaceutical research programs. MEDIOCON INC supplies premium-quality Mevastatin API to pharmaceutical manufacturers, contract research organizations (CROs), biotechnology companies, universities, research institutes, analytical laboratories, and other qualified industry users worldwide, supported with comprehensive documentation including COA, MSDS/SDS, technical data sheets, analytical documentation, and applicable product specifications.
| Parameter | Specification |
|---|---|
| Appearance | White to Light-Yellow Powder or Crystalline Solid |
| Identification | IR / HPLC / LC-MS Complies |
| Assay (HPLC) | NLT 98.0% |
| Loss on Drying | NMT 1.0% |
| Residue on Ignition | NMT 0.5% |
| Heavy Metals | NMT 20 ppm |
| Individual Impurity | NMT 0.5% |
| Total Impurities | NMT 1.0% |
| Water Content | NMT 1.0% |
| Melting Point | 151°C – 153°C |
| Solubility | Soluble in ethanol; practically insoluble in water |
Mediocon Inc is a GMP-certified API manufacturer and bulk pharmaceutical ingredient supplier based in Aurangabad, Maharashtra, India. We specialise in supplying Mevastatin API Manufacturer & Supplier in India | MEDIOCON INC (CAS 73573-88-3) and over 1,000 other Active Pharmaceutical Ingredients, excipients, herbal extracts, and nutraceutical ingredients to pharmaceutical manufacturers worldwide.
Our Mevastatin API Manufacturer & Supplier in India | MEDIOCON INC is manufactured under strict quality management protocols compliant with WHO-GMP, ISO 9001:2015, and major pharmacopoeial standards (IP, BP, USP, EP). Every batch undergoes full analytical testing before release with a Certificate of Analysis.
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